Zoekresultaten - "pyrimidine"

Discovery of a potent and selective cell division cycle 7 inhibitor from 6-(3-fluoropyridin-4-yl)thieno[3,2-d]pyrimidin-4(3H)-one derivatives as an orally active antitumor agent door Mingwei Fu, Min Ge, Wanxiang Yang, Chunchen Hu, Xiaowei Li, Yuanjiang Wang, Shaohua Gou

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Synthesis and biological evaluation of a series of 2-(((5-akly/aryl-1H-pyrazol-3-yl)methyl)thio)-5-alkyl-6-(cyclohexylmethyl)-pyrimidin-4(3H)-ones as potential HIV-1 inhibitors door Yumeng Wu, Chengrun Tang, Ruomei Rui, Liumeng Yang, Wei Ding, Jiangyuan Wang, Yiming Li, Christopher C. Lai, Yueping Wang, Ronghua Luo, Weilie Xiao, Hongbing Zhang, Yongtang Zheng, Yanping He

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Design, Synthesis and In Vitro Antimicrobial Activity of 6-(1<i>H</i>-Benzimidazol-2-yl)-3,5-dimethyl-4-oxo-2-thio-3,4-dihydrothieno[2,3-<i>d</i>]pyrimidines door Sergiy V. Vlasov, Olena D. Vlasova, Hanna I. Severina, Konstantin Yu. Krolenko, Oleksandr V. Borysov, Amjad Ibrahim M. Abu Sharkh, Vitaliy S. Vlasov, Victoriya A. Georgiyants

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p-TSA-promoted syntheses of 5H-benzo[h]thiazolo[2,3-b]quinazoline and indeno[1,2-d]thiazolo[3,2-a]pyrimidine analogs: molecular modeling and in vitro antitumor activity against hepatocellular carcinoma door Keshari AK, Singh AK, Raj V, Rai A, Trivedi P, Ghosh B, Kumar U, Rawat A, Kumar D, Saha S

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From Serendipity to Rational Identification of the 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-<i>d</i>]pyrimidin-4(3<i>H</i>)-one Core as a New Chemotype of AKT1 Inhibitors for Acute Myeloid Leukemia door Andrea Astolfi, Francesca Milano, Deborah Palazzotti, Jose Brea, Maria Chiara Pismataro, Mariangela Morlando, Oriana Tabarrini, Maria Isabel Loza, Serena Massari, Maria Paola Martelli, Maria Letizia Barreca

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Discovery of Novel Dual Adenosine A_2A and A₁ Receptor Antagonists with 1<i>H</i>-Pyrazolo[3,4<i>-d</i>]pyrimidin-6-amine Core Scaffold as Anti-Parkinson's Disease Agents door Juyoung Jung, Yoonsuk Lee, An-Na Moon, Jihyae Ann, Jin Ju Jeong, Nayeon Do, Jeewoo Lee

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Effective Activation of BK_Ca Channels by QO-40 (5-(Chloromethyl)-3-(Naphthalen-1-yl)-2-(Trifluoromethyl)Pyrazolo [1,5-a]pyrimidin-7(4<i>H</i>)-one), Known to Be an Opener of KCNQ2/Q3 Channels door Wei-Ting Chang, Sheng-Nan Wu

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Design and Synthesis of Novel <i>N</i>-Benzylidene Derivatives of 3-Amino-4-imino-3,5-dihydro-4<i>H</i>-chromeno[2,3-<i>d</i>]pyrimidine under Microwave, <i>In Silico</i> ADME Predictions, <i>In Vitro</i> Antitumoral Activities and <i>In Vivo</i> Toxicity door Sirine Karoui, Marwa Dhiabi, Mehdi Fakhfakh, Souhir Abid, Emmanuelle Limanton, Rémy Le Guével, Thierry D. Charlier, Anthony Mainguy, Olivier Mignen, Ludovic Paquin, Houcine Ammar, Jean-Pierre Bazureau

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Recent Advances in the Synthesis, Functionalization and Applications of Pyrazole-Type Compounds I

Onderwerpen: “…pyrazolo[1,5-a]pyrimidine…”
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Model-Based Tools for Pharmaceutical Manufacturing Processes door Gernaey, Krist V.

Onderwerpen: “…pyrimidine-nucleoside phosphorylase…”
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Pharmaceutical Crystals (Volume II)

Onderwerpen: “…pyrimidine…”
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Pharmaceutical Crystals (Volume II)

Onderwerpen: “…pyrimidine…”
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The Design, Synthesis, and Biological Evaluation of Compounds with Medicinal Value

Onderwerpen: “…pyrimidine-trione…”
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Pharmaceutical Crystals door Uekusa, Hidehiro

Onderwerpen: “…pyrimidin-4(3H)-one…”
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Herbicide Resistance in Plants

Onderwerpen: “…pyrimidine biosynthesis…”
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Synthesis of Heteroaromatic Compounds

Onderwerpen: “…pyrimidine…”
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Steroid Compounds with Potential Biological Activity

Onderwerpen: “…pyrimidines…”
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Nitrogen-Containing Molecules: Natural and Synthetic Products Including Coordination Compounds

Onderwerpen: “…pyrimidine…”
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Killing Cancer Discovery and Selection of New Target Molecules

Onderwerpen: “…pyrazolo-pyrimidine derivative…”
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Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach

Onderwerpen: “…cyclobutane-pyrimidine dimer (CPD) photolesion…”
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