Search Results - "structure–activity relationship"

Monosubstituted Acetophenone Thiosemicarbazones as Potent Inhibitors of Tyrosinase: Synthesis, Inhibitory Studies, and Molecular Docking by Katarzyna Hałdys, Waldemar Goldeman, Natalia Anger-Góra, Joanna Rossowska, Rafał Latajka

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Intratracheal Administration of siRNA Triggers mRNA Silencing in the Lung to Modulate T Cell Immune Response and Lung Inflammation by Bruce Ng, Tanesha Cash-Mason, Yi Wang, Jessica Seitzer, Julja Burchard, Duncan Brown, Vadim Dudkin, Joseph Davide, Vasant Jadhav, Laura Sepp-Lorenzino, Pedro J. Cejas

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Small-molecule MDM2/X inhibitors and PROTAC degraders for cancer therapy: advances and perspectives by Yuan Fang, Guochao Liao, Bin Yu

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An Explainable Supervised Machine Learning Model for Predicting Respiratory Toxicity of Chemicals Using Optimal Molecular Descriptors by Keerthana Jaganathan, Hilal Tayara, Kil To Chong

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The Development of Third-Generation Tetracycline Antibiotics and New Perspectives by Aura Rusu, Emanuela Lorena Buta

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Approaches to predict ligands affinity towards translocator protein TSPO 18 kDa in order to create molecules possessing neuropsychotropic activity by N. M. Baraboshkin, A. S. Pantileev, G. V. Mokrov

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QSAR and Molecular Docking Studies on Non-Imidazole-Based Histamine H3 Receptor Antagonists by Maryam Hamzeh-Mivehroud, Zoha Khoshravan-Azar, Siavoush Dastmalchi

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Evolution of the Quinoline Scaffold for the Treatment of Leishmaniasis: A Structural Perspective by Carlos F. M. Silva, Diana C. G. A. Pinto, Pedro A. Fernandes, Artur M. S. Silva

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Exploring the possible use of saponin adjuvants in COVID-19 vaccine by Rinku Sharma, Arivukarasu Palanisamy, Kuldeep Dhama, Gorakh Mal, Birbal Singh, Karam Pal Singh

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Psychoactive Drugs-From Chemical Structure to Oxidative Stress Related to Dopaminergic Neurotransmission. A Review by George Jîtcă, Bianca E. Ősz, Amelia Tero-Vescan, Camil E. Vari

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SAR Analysis of Small Molecules Interfering with Energy-Metabolism in <i>Mycobacterium tuberculosis</i> by Federico Appetecchia, Sara Consalvi, Cristina Scarpecci, Mariangela Biava, Giovanna Poce

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Design, synthesis, and biological evaluation of benzoheterocyclic sulfoxide derivatives as quorum sensing inhibitors in Pseudomonas aeruginosa by Shen Mao, Qiaoqiang Li, Zhikun Yang, Yasheng Li, Xinyi Ye, Hong Wang

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Thiazolidinedione an auspicious scaffold as PPAR-γ agonist: its possible mechanism to Manoeuvre against insulin resistant diabetes mellitus by Sourav Basak, Anjali Murmu, Balaji Wamanrao Matore, Partha Pratim Roy, Jagadish Singh

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Preventing Microbial Infections with Natural Phenolic Compounds by Kardelen Ecevit, Alexandre A. Barros, Joana M. Silva, Rui L. Reis

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Synthesis, molecular modelling and anticancer evaluation of new pyrrolo[1,2-b]pyridazine and pyrrolo[2,1-a]phthalazine derivatives by Lacramioara Popovici, Roxana-Maria Amarandi, Ionel I. Mangalagiu, Violeta Mangalagiu, Ramona Danac

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New Antifungal Agents with Azole Moieties by Melissa Martins Teixeira, Diogo Teixeira Carvalho, Emília Sousa, Eugénia Pinto

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Computational strategies for PROTAC drug discovery by Jia Wu, Wanhe Wang, Chung-Hang Leung

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Fluorinated Derivatives of Digalloyl-Flavan-3-ol Induce Autophagic Cell Death by Forming Granular Aggregates Containing Mitochondria by Ryo Doge, Yuki Nishino, Akiko Saito

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Relationships Between Chemical Structure and Antioxidant Activity of Isolated Phytocompounds from Lemon Verbena by Noelia Sánchez-Marzo, Jesús Lozano-Sánchez, María de la Luz Cádiz-Gurrea, María Herranz-López, Vicente Micol, Antonio Segura-Carretero

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Journey on Naphthoquinone and Anthraquinone Derivatives: New Insights in Alzheimer's Disease by Marta Campora, Valeria Francesconi, Silvia Schenone, Bruno Tasso, Michele Tonelli

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