Search Results - "structure–activity relationship"

Benzimidazole-Based Schiff Base Hybrid Scaffolds: A Promising Approach to Develop Multi-Target Drugs for Alzheimer's Disease by Rafaqat Hussain, Shoaib Khan, Hayat Ullah, Farhan Ali, Yousaf Khan, Asma Sardar, Rashid Iqbal, Farid S. Ataya, Nasser M. El-Sabbagh, Gaber El-Saber Batiha

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Multi-Target Actions of Acridones from <i>Atalantia monophylla</i> towards Alzheimer's Pathogenesis and Their Pharmacokinetic Properties by Pitchayakarn Takomthong, Pornthip Waiwut, Chavi Yenjai, Aonnicha Sombatsri, Prasert Reubroycharoen, Luo Lei, Ren Lai, Suchada Chaiwiwatrakul, Chantana Boonyarat

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Design, synthesis and α-glucosidase inhibition study of novel embelin derivatives by Xiaole Chen, Min Gao, Rongchao Jian, Weiqian David Hong, Xiaowen Tang, Yuling Li, Denggao Zhao, Kun Zhang, Wenhua Chen, Xi Zheng, Zhaojun Sheng, Panpan Wu

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Nitroaromatics as hypoxic cell radiosensitizers: A 2D-QSAR approach to explore structural features contributing to radiosensitization effectiveness by Priyanka De, Kunal Roy

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The prospects for the use of vitamin B12 derivatives in pharmacology by I. Yu. Torshin, O. A. Gromova, L. A. Maiorova

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Evaluation of Amyloid Polypeptide Aggregation Inhibition and Disaggregation Activity of A-Type Procyanidins by Taisei Tanaka, Vipul V. Betkekar, Ken Ohmori, Keisuke Suzuki, Hideyuki Shigemori

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Tertiary amine derivatives of chlorochalcone as acetylcholinesterase (AChE) and buthylcholinesterase (BuChE) inhibitors: the influence of chlorine, alkyl amine side chain and α,β-u... by Xiao-hui Gao, Chao Zhou, Hao-ran Liu, Lin-bo Liu, Jing-jing Tang, Xin-hua Xia

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From Erythromycin to Azithromycin and New Potential Ribosome-Binding Antimicrobials by Dubravko Jelić, Roberto Antolović

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Discovery of Novel Inhibitors of Indoleamine 2,3-Dioxygenase 1 Through Structure-Based Virtual Screening by Guoqing Zhang, Guoqing Zhang, Jing Xing, Jing Xing, Yulan Wang, Yulan Wang, Lihao Wang, Yan Ye, Yan Ye, Dong Lu, Dong Lu, Jihui Zhao, Jihui Zhao, Xiaomin Luo, Mingyue Zheng, Shiying Yan

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Novel tacrine-benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer's Disease by Gaia Fancellu, Karam Chand, Daniel Tomás, Elisabetta Orlandini, Luca Piemontese, Diana F. Silva, Sandra M. Cardoso, Sílvia Chaves, M. Amélia Santos

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How Does the Phenol Structure Influence the Results of the Folin-Ciocalteu Assay? by Melanie Platzer, Sandra Kiese, Thomas Herfellner, Ute Schweiggert-Weisz, Peter Eisner

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Phenotypic Screen Identifies a Small Molecule Modulating ERK2 and Promoting Stem Cell Proliferation by Chang Yin, Chang Yin, Temesgen Fufa, Temesgen Fufa, Gayathri Chandrasekar, Gayathri Chandrasekar, Madhu Aeluri, Madhu Aeluri, Verina Zaky, Shaimaa Abdelhady, Antonio B. Rodríguez, Johan Jakobsson, Farzaneh Shahin Varnoosfaderani, Jayashri Mahalingam, Jianping Liu, Olle Larsson, Outi Hovatta, Frank Gaunitz, Anita Göndör, Michael Andäng, Satish S. Kitambi

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Expanding the inhibitor space of the WWP1 and WWP2 HECT E3 ligases by Ashley P. Dudey, Jake M. Rigby, Gregory R. Hughes, G. Richard Stephenson, Thomas E. Storr, Andrew Chantry, Andrew M. Hemmings

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Computational modeling and ligand-based design of some novel hypothetical compound as prominent inhibitors against Mycobacterium tuberculosis by Shola Elijah Adeniji, Olajumoke Bosede Adalumo

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Design, synthesis, molecular modeling, and biological evaluation of acrylamide derivatives as potent inhibitors of human dihydroorotate dehydrogenase for the treatment of rheumatoi... by Fanxun Zeng, Shiliang Li, Guantian Yang, Yating Luo, Tiantian Qi, Yingfan Liang, Tingyuan Yang, Letian Zhang, Rui Wang, Lili Zhu, Honglin Li, Xiaoyong Xu

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Inhibition of Osteoclast Differentiation by Carotenoid Derivatives through Inhibition of the NF-κB Pathway by Shlomit Odes-Barth, Marina Khanin, Karin Linnewiel-Hermoni, Yifat Miller, Karina Abramov, Joseph Levy, Yoav Sharoni

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Investigation on the in vitro antioxidant capacity of methanol extract, fractions and flavones from Oroxylum indicum Linn bark by Do Hoang Thu Trang, Hoang Le Son, Phung Van Trung

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Identifying FAAH Inhibitors as New Therapeutic Options for the Treatment of Chronic Pain through Drug Repurposing by Anca Zanfirescu, Georgiana Nitulescu, Dragos Paul Mihai, George Mihai Nitulescu

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Antimicrobial Activities and Mode of Flavonoid Actions by Amal Thebti, Ahmed Meddeb, Issam Ben Salem, Coulibaly Bakary, Sami Ayari, Farhat Rezgui, Khadija Essafi-Benkhadir, Abdellatif Boudabous, Hadda-Imene Ouzari

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Uracil as a Zn-Binding Bioisostere of the Allergic Benzenesulfonamide in the Design of Quinoline-Uracil Hybrids as Anticancer Carbonic Anhydrase Inhibitors by Samar A. El-Kalyoubi, Ehab S. Taher, Tarek S. Ibrahim, Mohammed Farrag El-Behairy, Amany M. M. Al-Mahmoudy

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