Search Results - "structure–activity relationship"

RAID: Regression Analysis-Based Inductive DNA Microarray for Precise Read-Across by Yuto Amano, Masayuki Yamane, Hiroshi Honda

Connect to this object online.

Design of new disubstituted imidazo[1,2-b]pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation by Jonathan Elie, Omid Feizbakhsh, Nathalie Desban, Béatrice Josselin, Blandine Baratte, Amandine Bescond, Julien Duez, Xavier Fant, Stéphane Bach, Dominique Marie, Matthieu Place, Sami Ben Salah, Agnes Chartier, Sabine Berteina-Raboin, Apirat Chaikuad, Stefan Knapp, Fabrice Carles, Pascal Bonnet, Frédéric Buron, Sylvain Routier, Sandrine Ruchaud

Connect to this object online.

Synthesis and Biological Activity of Piperidinothiosemicarbazones Derived from Aminoazinecarbonitriles by Dagmara Ziembicka, Katarzyna Gobis, Małgorzata Szczesio, Ewa Augustynowicz-Kopeć, Agnieszka Głogowska, Izabela Korona-Głowniak, Krzysztof Bojanowski

Connect to this object online.

Targeting castration-resistant prostate cancer with a novel RORγ antagonist elaiophylin by Jianwei Zheng, Junfeng Wang, Qian Wang, Hongye Zou, Hong Wang, Zhenhua Zhang, Jianghe Chen, Qianqian Wang, Panxia Wang, Yueshan Zhao, Jing Lu, Xiaolei Zhang, Songtao Xiang, Haibin Wang, Jinping Lei, Hong-Wu Chen, Peiqing Liu, Yonghong Liu, Fanghai Han, Junjian Wang

Connect to this object online.

Transporter-Mediated Drug Interaction Strategy for 5-Aminolevulinic Acid (ALA)-Based Photodynamic Diagnosis of Malignant Brain Tumor: Molecular Design of ABCG2 Inhibitors by Toshihisa Ishikawa, Shin-ichi Miyatake, Toshihiko Kuroiwa, Shun-ichiro Ogura, Yuichiro Hagiya, Yoshinaga Kajimoto, Naokado Ikeda, Kenkichi Takahashi

Connect to this object online.

A Kinetic Approach to Oxygen Radical Absorbance Capacity (ORAC): Restoring Order to the Antioxidant Activity of Hydroxycinnamic Acids and Fruit Juices by Umme Asma, Maria Letizia Bertotti, Simone Zamai, Marcellus Arnold, Riccardo Amorati, Matteo Scampicchio

Connect to this object online.

Pharmacological evaluation of enantiomerically separated positive allosteric modulators of cannabinoid 1 receptor, GAT591 and GAT593 by Asher L. Brandt, Sumanta Garai, Ayat Zagzoog, Dow P. Hurst, Lesley A. Stevenson, Roger G. Pertwee, Gregory H. Imler, Patricia H. Reggio, Ganesh A. Thakur, Robert B. Laprairie, Robert B. Laprairie

Connect to this object online.

Investigation of piperazines as human carbonic anhydrase I, II, IV and VII activators by Andrea Angeli, Niccolò Chiaramonte, Dina Manetti, Maria Novella Romanelli, Claudiu T. Supuran

Connect to this object online.

Halogenated Pyrrolopyrimidines with Low MIC on <i>Staphylococcus aureus</i> and Synergistic Effects with an Antimicrobial Peptide by Cecilie Elisabeth Olsen, Fredrik Heen Blindheim, Caroline Krogh Søgaard, Lisa Marie Røst, Amanda Holstad Singleton, Olaug Elisabeth Torheim Bergum, Per Bruheim, Marit Otterlei, Eirik Sundby, Bård Helge Hoff

Connect to this object online.

Novel Dichloroacetophenone-Based PDHK1 Inhibitors as Potent Anticancer Agents by Wu P, Zhang Z, Zhou Y, Liu Q, Tam KY, Su Z

Connect to this object online.

Phytochemical Analysis and Anti-Biofilm Potential That Cause Dental Caries from Black Cumin Seeds (Nigella sativa Linn.) by Kurnia D, Padilah R, Apriyanti E, Dharsono HDA

Connect to this object online.

Design of Potent Inhibitors Targeting the Main Protease of SARS-CoV-2 Using QSAR Modeling, Molecular Docking, and Molecular Dynamics Simulations by Mehdi Oubahmane, Ismail Hdoufane, Christelle Delaite, Adlane Sayede, Driss Cherqaoui, Achraf El Allali

Connect to this object online.

Structure Optimization of 12β-<em>O</em>-γ-Glutamyl Oleanolic Acid Derivatives Resulting in Potent FXR Antagonist/Modulator for NASH Therapy by Hao Ma, Yunyang Bao, Shuaishuai Niu, Shaorong Wang, Yiming Li, Hongwei He, Na Zhang, Weishuo Fang

Connect to this object online.

Potential Valorization of Edible Nuts By-Products: Exploring the Immune-Modulatory and Antioxidants Effects of Selected Nut Shells Extracts in Relation to Their Metabolic Profiles by Mohamed A. Salem, Nora M. Aborehab, Ahmed A. Al-Karmalawy, Alisdair R. Fernie, Saleh Alseekh, Shahira M. Ezzat

Connect to this object online.

Exploring the Prominent and Concealed Inhibitory Features for Cytoplasmic Isoforms of Hsp90 Using QSAR Analysis by Magdi E. A. Zaki, Sami A. Al-Hussain, Syed Nasir Abbas Bukhari, Vijay H. Masand, Mithilesh M. Rathore, Sumer D. Thakur, Vaishali M. Patil

Connect to this object online.

Synthesis and biological evaluation of ortho-phenyl phenylhydroxamic acids containing phenothiazine with improved selectivity for class IIa histone deacetylases by Kai-Cheng Hsu, Yun-Yi Huang, Jung-Chun Chu, Yu-Wen Huang, Jing-Lan Hu, Tony Eight Lin, Shih-Chung Yen, Jing-Ru Weng, Wei-Jan Huang

Connect to this object online.

6-Amino-2,4,5-trimethylpyridin-3-ol and 2-amino-4,6-dimethylpyrimidin-5-ol derivatives as selective fibroblast growth factor receptor 4 inhibitors: design, synthesis, molecular doc... by Chhabi Lal Chaudhary, Dongchul Lim, Prakash Chaudhary, Diwakar Guragain, Bhuwan Prasad Awasthi, Hee Dong Park, Jung-Ae Kim, Byeong-Seon Jeong

Connect to this object online.

Anti-proliferative Effects of a Coumarin Benjaminin on Four Human Cancer Cell Lines by Siau Hui Mah, Soek Sin Teh, Ahmad Azri Fitri Ismail, Gwendoline Cheng Lian Ee

Connect to this object online.

Novel N7-Arylmethyl Substituted Dinucleotide mRNA 5' cap Analogs: Synthesis and Evaluation as Modulators of Translation by Radoslaw Wojcik, Marek R. Baranowski, Lukasz Markiewicz, Dorota Kubacka, Marcelina Bednarczyk, Natalia Baran, Anna Wojtczak, Pawel J. Sikorski, Joanna Zuberek, Joanna Kowalska, Jacek Jemielity

Connect to this object online.

Exploring novel natural compound-based therapies for Duchenne muscular dystrophy management: insights from network pharmacology, QSAR modeling, molecular dynamics, and free energy... by Mohd Saeed, Ashanul Haque, Ambreen Shoaib, Syed Mohd Danish Rizvi

Connect to this object online.