Search Results - "structure–activity relationship"

Molecular Insights into Coumarin Analogues as Antimicrobial Agents: Recent Developments in Drug Discovery by Rameshwar S. Cheke, Harun M. Patel, Vaishali M. Patil, Iqrar Ahmad Ansari, Jaya P. Ambhore, Sachin D. Shinde, Adel Kadri, Mejdi Snoussi, Mohd Adnan, Prashant S. Kharkar, Visweswara Rao Pasupuleti, Prashant K. Deshmukh

Connect to this object online.

Design, synthesis and pharmacological evaluation of 4-(3-chloro-4-(3-cyclopropylthioureido)-2-fluorophenoxy)-7-methoxyquinoline-6-carboxamide (WXFL-152): a novel triple angiokinase... by Yuqin Yao, Zhuowei Liu, Manyu Zhao, Zhengxia Chen, Peng Li, Yang Zhang, Yuxi Wang, Chengjian Zhao, Chaofeng Long, Xiaoxin Chen, Jinliang Yang

Connect to this object online.

Design and statistical optimisation of emulsomal nanoparticles for improved anti-SARS-CoV-2 activity of N-(5-nitrothiazol-2-yl)-carboxamido candidates: in vitro and in silico studi... by Ahmed A. Al-Karmalawy, Dalia S. El-Gamil, Rabeh El-Shesheny, Marwa Sharaky, Radwan Alnajjar, Omnia Kutkat, Yassmin Moatasim, Mohamed Elagawany, Sara T. Al-Rashood, Faizah A. Binjubair, Wagdy M. Eldehna, Ayman M. Noreddin, Mohamed Y. Zakaria

Connect to this object online.

Identification of flavonolignans from Silybum marianum seeds as allosteric protein tyrosine phosphatase 1B inhibitors by Ningbo Qin, Tatsunori Sasaki, Wei Li, Jian Wang, Xiangyu Zhang, Dahong Li, Zhanlin Li, Maosheng Cheng, Huiming Hua, Kazuo Koike

Connect to this object online.

Structure-based discovery of orally efficient inhibitors via unique interactions with H-pocket of PDE8 for the treatment of vascular dementia by Xu-Nian Wu, Qian Zhou, Ya-Dan Huang, Xi Xie, Zhe Li, Yinuo Wu, Hai-Bin Luo

Connect to this object online.

Quantitative Structure-Toxicity Relationship in Bioactive Molecules from a Conceptual DFT Perspective by Ranita Pal, Shanti Gopal Patra, Pratim Kumar Chattaraj

Connect to this object online.

<i>Staphylococcus aureus</i> RnpA Inhibitors: Computational-Guided Design, Synthesis and Initial Biological Evaluation by Lorenzo Suigo, Michaelle Chojnacki, Carlo Zanotto, Victor Sebastián-Pérez, Carlo De Giuli Morghen, Andrea Casiraghi, Paul M. Dunman, Ermanno Valoti, Valentina Straniero

Connect to this object online.

Cell-Penetrating Dabcyl-Containing Tetraarginines with Backbone Aromatics as Uptake Enhancers by Mo'ath Yousef, Ildikó Szabó, József Murányi, Françoise Illien, Dóra Soltész, Csaba Bató, Gabriella Tóth, Gyula Batta, Péter Nagy, Sandrine Sagan, Zoltán Bánóczi

Connect to this object online.

Design, synthesis and biological evaluation of tricyclic pyrazolo[1,5-c][1,3]benzoxazin-5(5H)-one scaffolds as selective BuChE inhibitors by Guo-Liang Qiu, Shao-Sheng He, Shi-Chao Chen, Bo Li, Hui-Hui Wu, Jing Zhang, Wen-Jian Tang

Connect to this object online.

An Antibacterial Peptide with High Resistance to Trypsin Obtained by Substituting <span style="font-variant: small-caps">d</span>-Amino Acids for Trypsin Cleavage Sites by Xiaoou Zhao, Mengna Zhang, Inam Muhammad, Qi Cui, Haipeng Zhang, Yu Jia, Qijun Xu, Lingcong Kong, Hongxia Ma

Connect to this object online.

QSAR-Based Virtual Screening: Advances and Applications in Drug Discovery by Bruno J. Neves, Bruno J. Neves, Rodolpho C. Braga, Cleber C. Melo-Filho, José Teófilo Moreira-Filho, Eugene N. Muratov, Eugene N. Muratov, Carolina Horta Andrade

Connect to this object online.

Discovery of Quercetin and Its Analogs as Potent OXA-48 Beta-Lactamase Inhibitors by Yuejuan Zhang, Yuejuan Zhang, Cheng Chen, Bin Cheng, Lei Gao, Lei Gao, Chuan Qin, Chuan Qin, Lixia Zhang, Xu Zhang, Xu Zhang, Jun Wang, Jun Wang, Yi Wan, Yi Wan

Connect to this object online.

Recent Progress in Synthesis, POM Analyses and SAR of Coumarin-Hybrids as Potential Anti-HIV Agents-A Mini Review by Mustapha Suleiman, Faisal A. Almalki, Taibi Ben Hadda, Sarkar M. A. Kawsar, Subhash Chander, Sankaranarayanan Murugesan, Ajmal R. Bhat, Andrey Bogoyavlenskiy, Joazaizulfazli Jamalis

Connect to this object online.

Discovery of novel 4-phenylquinazoline-based BRD4 inhibitors for cardiac fibrosis by Zhangxu He, Haomiao Jiao, Qi An, Xin Zhang, Dan Zengyangzong, Jiale Xu, Hongmin Liu, Liying Ma, Wen Zhao

Connect to this object online.

Design and Synthesis of Novel Amino and Acetamidoaurones with Antimicrobial Activities by Attilio Di Maio, Hamza Olleik, Elise Courvoisier-Dezord, Sophie Guillier, Fabienne Neulat-Ripoll, Romain Haudecoeur, Jean-Michel Bolla, Magali Casanova, Jean-François Cavalier, Stéphane Canaan, Valérie Pique, Yolande Charmasson, Elias Baydoun, Akram Hijazi, Josette Perrier, Marc Maresca, Maxime Robin

Connect to this object online.

2-Phenoxy-3-Trichloromethylquinoxalines Are Antiplasmodial Derivatives with Activity against the Apicoplast of <i>Plasmodium falciparum</i> by Dyhia Amrane, Christophe-Sébastien Arnold, Sébastien Hutter, Julen Sanz-Serrano, Miguel Collia, Amaya Azqueta, Lucie Paloque, Anita Cohen, Nadia Amanzougaghene, Shahin Tajeri, Jean-François Franetich, Dominique Mazier, Françoise Benoit-Vical, Pierre Verhaeghe, Nadine Azas, Patrice Vanelle, Cyrille Botté, Nicolas Primas

Connect to this object online.

The Cactus (<i>Opuntia ficus-indica</i>) Cladodes and Callus Extracts: A Study Combined with LC-MS Metabolic Profiling, In-Silico, and In-Vitro Analyses by Dong-Geon Nam, Hee-Sun Yang, Ui-Jin Bae, Eunmi Park, Ae-Jin Choi, Jeong-Sook Choe

Connect to this object online.

Discovery of 4-arylthiophene-3-carboxylic acid as inhibitor of ANO1 and its effect as analgesic agent by Yuxi Wang, Jian Gao, Song Zhao, Yan Song, Han Huang, Guiwang Zhu, Peili Jiao, Xiangqing Xu, Guisen Zhang, Kewei Wang, Liangren Zhang, Zhenming Liu

Connect to this object online.

Design and Synthesis of Novel Symmetric Fluorene-2,7-Diamine Derivatives as Potent Hepatitis C Virus Inhibitors by Mai H. A. Mousa, Nermin S. Ahmed, Kai Schwedtmann, Efseveia Frakolaki, Niki Vassilaki, Grigoris Zoidis, Jan J. Weigand, Ashraf H. Abadi

Connect to this object online.

A targeted covalent inhibitor of p97 with proteome-wide selectivity by Zi Ye, Ke Wang, Lianguo Chen, Xiaofeng Jin, Hao Chen, Guanghui Tang, Shao Q. Yao, Zhiqiang Feng, Chong-Jing Zhang

Connect to this object online.