Search Results - "structure–activity relationship"

Characterization of the metabolism of eupalinolide A and B by carboxylesterase and cytochrome P450 in human liver microsomes by Yingzi Li, Xiaoyan Liu, Ludi Li, Tao Zhang, Yadong Gao, Kewu Zeng, Qi Wang, Qi Wang, Qi Wang

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Recent developments of phosphodiesterase inhibitors: Clinical trials, emerging indications and novel molecules by Andrey D. Bondarev, Misty M. Attwood, Jörgen Jonsson, Vladimir N. Chubarev, Vadim V. Tarasov, Wen Liu, Helgi B. Schiöth

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Design of semisynthetic derivatives of the Amaryllidaceae alkaloid ambelline and exploration of their in vitro cytotoxic activities by Aneta Ritomská, Darja Koutova, Jana Křoustková, Karel Královec, Darina Muthná, Jiří Kuneš, Lucie Nováková, Radim Havelek, Lucie Cahlíková

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Derivation of Highly Predictive 3D-QSAR Models for hERG Channel Blockers Based on the Quantum Artificial Neural Network Algorithm by Taeho Kim, Kee-Choo Chung, Hwangseo Park

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Design and synthesis of quinazoline carboxylates against Gram-positive, Gram-negative, fungal pathogenic strains, and Mycobacterium tuberculosis by Theivendren Panneer Selvam, Arumugam Sivakumar, Padmavathi P Prabhu

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Design, Synthesis, and Repurposing of Rosmarinic Acid-β-Amino-α-Ketoamide Hybrids as Antileishmanial Agents by Ahmed H.E. Hassan, Waleed A. Bayoumi, Selwan M. El-Sayed, Trong-Nhat Phan, Taegeun Oh, Gyeongpyo Ham, Kazem Mahmoud, Joo Hwan No, Yong Sup Lee

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Lipoxygenase Inhibition Activity of Coumarin Derivatives-QSAR and Molecular Docking Study by Melita Lončarić, Ivica Strelec, Valentina Pavić, Domagoj Šubarić, Vesna Rastija, Maja Molnar

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Pharmacokinetic evaluation, molecular docking and in vitro biological evaluation of 1, 3, 4-oxadiazole derivatives as potent antioxidants and STAT3 inhibitors by Rashmin khanam, Iram I. Hejazi, Syed Shahabuddin, Abdul R. Bhat, Fareeda Athar

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Synthesis of a new series of 3-functionalised-1-phenyl-1,2,3-triazole sulfamoylbenzamides as carbonic anhydrase I, II, IV and IX inhibitors by Baijayantimala Swain, Andrea Angeli, Srinivas Angapelly, Pavitra S. Thacker, Priti Singh, Claudiu T. Supuran, Mohammed Arifuddin

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Discovery, synthesis and antibacterial evaluation of phenolic compounds from Cylicodiscus gabunensis by Omar Aldulaimi, Falko Drijfhout, Fidelia I. Uche, Paul Horrocks, Wen-Wu Li

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Relationship Between the Structure and Immune Activity of Components From the Active Polysaccharides APS-II of Astragali Radix by Enzymolysis of Endo α-1,4-Glucanase by Ke Li, Ke Li, Ke Li, Ke Li, Xue-qin Li, Xue-qin Li, Xue-qin Li, Guang-xin Li, Lian-jie Cui, Lian-jie Cui, Lian-jie Cui, Xue-mei Qin, Xue-mei Qin, Xue-mei Qin, Zhen-yu Li, Zhen-yu Li, Zhen-yu Li, Yu-guang Du, Yue-tao Liu, Yue-tao Liu, Yue-tao Liu, Ai-ping Li, Ai-ping Li, Ai-ping Li, Xing-yun Zhao, Xing-yun Zhao, Xing-yun Zhao, Xin-hui Fan, Xin-hui Fan, Xin-hui Fan

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New 3-O-substituted xanthone derivatives as promising acetylcholinesterase inhibitors by Zi Han Loh, Huey Chong Kwong, Kok Wai Lam, Soek Sin Teh, Gwendoline Cheng Lian Ee, Ching Kheng Quah, Anthony Siong Hock Ho, Siau Hui Mah

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Matrix metalloproteinases and their considerations in Dentistry from the field of computational chemistry by Antonio José Díaz Caballero, Darío Mendez Cuadro, Emiliano Rafael Martinez Serrano, Jennifer Orozco Páez, Margarita Rosa Velásquez Martínez

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An Alignment-Independent 3D-QSAR Study of FGFR2 Tyrosine Kinase Inhibitors by Behzad Jafari, Maryam Hamzeh-Mivehroud, Ali Akbar Alizadeh, Mehdi Sharifi, Siavoush Dastmalchi

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Structurally optimized analogs of the retrograde trafficking inhibitor Retro-2cycl limit Leishmania infections. by Evan Craig, Charles-Eugene Hu, Chun Yu, Emma L Handy, Jason K Sello, Peter E Kima

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Focus on the high therapeutic potentials of quercetin and its derivatives by Axelle Septembre-Malaterre, Ahcène Boumendjel, Anne-Laure Sandenon Seteyen, Chailas Boina, Philippe Gasque, Pascale Guiraud, Jimmy Sélambarom

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A novel non-linear approach for establishing a QSAR model of a class of 2-Phenyl-3-(pyridin-2-yl) thiazolidin-4-one derivatives by Leilei Wu, Yonglin Chen, Kangying Duan

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Identification of Small Molecule Inhibitors of <i>Staphylococcus aureus</i> RnpA by Jennifer M. Colquhoun, Lisha Ha, Andrew Beckley, Brinkley Meyers, Daniel P. Flaherty, Paul M. Dunman

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Why 90% of clinical drug development fails and how to improve it? by Duxin Sun, Wei Gao, Hongxiang Hu, Simon Zhou

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QSAR and docking studies on xanthone derivatives for anticancer activity targeting DNA topoisomerase II&alpha; by Alam S, Khan F

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