Search Results - "structure–activity relationship"

Goondapyrones A-J: Polyketide α and γ Pyrone Anthelmintics from an Australian Soil-Derived <i>Streptomyces</i> sp. by Shengbin Jin, David F. Bruhn, Cynthia T. Childs, Erica Burkman, Yovany Moreno, Angela A. Salim, Zeinab G. Khalil, Robert J. Capon

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Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide... by Romeo Romagnoli, Tiziano De Ventura, Stefano Manfredini, Erika Baldini, Claudiu T. Supuran, Alessio Nocentini, Andrea Brancale, Carmine Varricchio, Roberta Bortolozzi, Lorenzo Manfreda, Giampietro Viola

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Evaluation of Chemical Compositions and the Antioxidant and Cytotoxic Properties of the Aqueous Extract of Tri-Yannarose Recipe (<i>Areca catechu</i>, <i>Azadirachta indica</i>, an... by Sineenart Sanpinit, Palika Wetchakul, Piriya Chonsut, Nuntika Prommee, Chuchard Punsawad, Jaehong Han, Soiphet Net-anong

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A cell-based fascin bioassay identifies compounds with potential anti-metastasis or cognition-enhancing functions by Robert Kraft, Allon Kahn, José L. Medina-Franco, Mikayla L. Orlowski, Cayla Baynes, Fabian López-Vallejo, Kobus Barnard, Gerald M. Maggiora, Linda L. Restifo

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Lignosulfonic Acid Sodium Is a Noncompetitive Inhibitor of Human Factor XIa by Srabani Kar, Page Bankston, Daniel K. Afosah, Rami A. Al-Horani

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Synthesis of new series of pyrimidine nucleoside derivatives bearing the acyl moieties as potential antimicrobial agents by Md Z. H. Bulbul, Tasneem S. Chowdhury, Md M. H. Misbah, Jannatul Ferdous, Sujan Dey, Imtiaj Hasan, Yuki Fujii, Yasuhiro Ozeki, Sarkar M. A. Kawsar

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The Effects of Flavonol and Flavone Glucuronides from <i>Potentilla chinensis</i> Leaves on TNF-α-Exposed Normal Human Dermal Fibroblasts by Yea Jung Choi, So Young Lee, So-Ri Son, Jun Yeon Park, Dae Sik Jang, Sullim Lee

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Improving Aqueous Solubility and In Vitro Pharmacokinetic Properties of the 3-Nitroimidazo[1,2-<i>a</i>]pyridine Antileishmanial Pharmacophore by Romain Paoli-Lombardo, Nicolas Primas, Sandra Bourgeade-Delmas, Sébastien Hutter, Alix Sournia-Saquet, Clotilde Boudot, Emilie Brenot, Caroline Castera-Ducros, Sophie Corvaisier, Marc Since, Aurélie Malzert-Fréon, Bertrand Courtioux, Alexis Valentin, Pierre Verhaeghe, Nadine Azas, Pascal Rathelot, Patrice Vanelle

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Discovery of Guanfacine as a Novel TAAR1 Agonist: A Combination Strategy through Molecular Modeling Studies and Biological Assays by Elena Cichero, Valeria Francesconi, Beatrice Casini, Monica Casale, Evgeny Kanov, Andrey S. Gerasimov, Ilya Sukhanov, Artem Savchenko, Stefano Espinoza, Raul R. Gainetdinov, Michele Tonelli

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Biologically Potent Benzimidazole-Based-Substituted Benzaldehyde Derivatives as Potent Inhibitors for Alzheimer's Disease along with Molecular Docking Study by Bushra Adalat, Fazal Rahim, Wajid Rehman, Zarshad Ali, Liaqat Rasheed, Yousaf Khan, Thoraya A. Farghaly, Sulaiman Shams, Muhammad Taha, Abdul Wadood, Syed A. A. Shah, Magda H. Abdellatif

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Discovery of thiosemicarbazone derivatives as effective New Delhi metallo-β-lactamase-1 (NDM-1) inhibitors against NDM-1 producing clinical isolates by Bing Zhao, Xinhui Zhang, Tingting Yu, Ying Liu, Xiaoling Zhang, Yongfang Yao, Xuejian Feng, Hongmin Liu, Dequan Yu, Liying Ma, Shangshang Qin

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Novel Chlorin e6-Curcumin Derivatives as a Potential Photosensitizer: Synthesis, Characterization, and Anticancer Activity by Til Bahadur Thapa Magar, Jusuk Lee, Ji Hoon Lee, Juhee Jeon, Pallavi Gurung, Junmo Lim, Yong-Wan Kim

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Raging the War Against Inflammation With Natural Products by Ali Attiq, Juriyati Jalil, Khairana Husain, Waqas Ahmad

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Bioactivity of Novel Pyrazole-Thiazolines Scaffolds against <i>Trypanosoma cruzi</i>: Computational Approaches and 3D Spheroid Model on Drug Discovery for Chagas Disease by Leonardo da Silva Lara, Guilherme Curty Lechuga, Lorraine Martins Rocha Orlando, Byanca Silva Ferreira, Bernardo Araújo Souto, Maurício Silva dos Santos, Mirian Claudia de Souza Pereira

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Low Concentrations of Oxidized Phospholipids Increase Stress Tolerance of Endothelial Cells by Christina Mauerhofer, Taras Afonyushkin, Olga V. Oskolkova, Klara Hellauer, Bernd Gesslbauer, Jasmin Schmerda, Yunbo Ke, Andreas Zimmer, Anna A. Birukova, Konstantin G. Birukov, Valery Bochkov

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Potential Implications of Hyperoside on Oxidative Stress-Induced Human Diseases: A Comprehensive Review by Wang K, Zhang H, Yuan L, Li X, Cai Y

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The SAR analysis of dietary polyphenols and their antagonistic effects on bortezomib at physiological concentrations by Tran Tran Thi Van, Tran Tran Thi Van, Hsun-Shuo Chang, Hsun-Shuo Chang, Hsun-Shuo Chang, Hsun-Shuo Chang, Ho-Cheng Wu, Ho-Cheng Wu, Chung-Kuang Lu, Chung-Kuang Lu, Hui-Chi Huang, Michal Korinek, Hui-Hua Hsiao, Hui-Hua Hsiao, Hui-Hua Hsiao, Chia-Hung Yen, Chia-Hung Yen, Chia-Hung Yen

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An Integrated Approach to Characterize Intestinal Metabolites of Four Phenylethanoid Glycosides and Intestinal Microbe-Mediated Antioxidant Activity Evaluation In Vitro Using UHPLC... by Xiaoming Wang, Xiaoyan Chang, Xiaomei Luo, Meifeng Su, Rong Xu, Jun Chen, Yi Ding, Yue Shi

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A novel ω-conotoxin Bu8 inhibiting N-type voltage-gated calcium channels displays potent analgesic activity by Jinqin Chen, Xinhong Liu, Shuo Yu, Jia Liu, Rongfang Chen, Yunxiao Zhang, Ling Jiang, Qiuyun Dai

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Exploring the hydrophobic channel of NNIBP leads to the discovery of novel piperidine-substituted thiophene[3,2-d]pyrimidine derivatives as potent HIV-1 NNRTIs by Dongwei Kang, Da Feng, Tiziana Ginex, Jinmi Zou, Fenju Wei, Tong Zhao, Boshi Huang, Yanying Sun, Samuel Desta, Erik De Clercq, Christophe Pannecouque, Peng Zhan, Xinyong Liu

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