Search Results - "structure–activity relationship"

Predictive QSAR model confirms flavonoids in Chinese medicine can activate voltage-gated calcium (CaV) channel in osteogenesis by Ki Chan, Henry Chi Ming Leung, James Kit-Hon Tsoi

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Design, synthesis, and biological evaluation of novel EF24 and EF31 analogs as potential IκB kinase β inhibitors for the treatment of pancreatic cancer by Xie X, Tu J, You H, Hu B

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Characterization and Stability of the Antimony-Quercetin Complex by Valcilaine Teixeira Barbosa, Janaína Barros de Menezes, Josué Carinhanha Caldas Santos, Maria Lysete de Assis Bastos, João Xavier de Araújo-Júnior, Ticiano Gomes do Nascimento, Irinaldo Diniz Basílio-Júnior, Luciano Aparecido Meireles Grillo, Camila Braga Dornelas

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Flavonoids from <i>Selaginella doederleinii</i> Hieron and Their Antioxidant and Antiproliferative Activities by Felix Wambua Muema, Ye Liu, Yongli Zhang, Guilin Chen, Mingquan Guo

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Development of QSAR models for in silico screening of antibody solubility by Xuan Han, James Shih, Yuhao Lin, Qing Chai, Steven M. Cramer

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Phytochemistry-five decades of research in Africa: A bibliometric analysis by Adeiza Shuaibu Suleiman, Mansur Lawal, Shaibu Adona Sadiku

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Evaluation of antitumor potential of synthesized novel 2-substituted 4-anilinoquinazolines as quinazoline-pyrrole hybrids in MCF-7 human breast cancer cell line and A-549 human lun... by Raju Bathula, Presenjit Mondal, Ramakrishna Raparla, Shobha Rani Satla

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Monastrol derivatives: in silico and in vitro cytotoxicity assessments by Zahra Bidram, Hajar Sirous, Ghadam Ali Khodarahmi, Farshid Hassanzadeh, Nasim Dana, Amir Ali Hariri, Mahboubeh Rostami

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Pyrazole-Curcumin Suppresses Cardiomyocyte Hypertrophy by Disrupting the CDK9/CyclinT1 Complex by Masafumi Funamoto, Yoichi Sunagawa, Mai Gempei, Kana Shimizu, Yasufumi Katanasaka, Satoshi Shimizu, Toshihide Hamabe-Horiike, Giovanni Appendino, Alberto Minassi, Andreas Koeberle, Maki Komiyama, Kiyoshi Mori, Koji Hasegawa, Tatsuya Morimoto

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Initial Development of Automated Machine Learning-Assisted Prediction Tools for Aryl Hydrocarbon Receptor Activators by Paulina Anna Wojtyło, Natalia Łapińska, Lucia Bellagamba, Emidio Camaioni, Aleksander Mendyk, Stefano Giovagnoli

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Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells by Romeo Romagnoli, Filippo Prencipe, Luisa Carlota Lopez-Cara, Paola Oliva, Stefania Baraldi, Pier Giovanni Baraldi, Francisco Estévez-Sarmiento, José Quintana, Francisco Estévez

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Synthesis and cytotoxicity evaluation of novel cyclic/non-cyclic N-aryl enamino amides against human cancer cell lines by Shahab Bohlooli, Negin Nejatkhah, Saghi Sepehri, Donya Doostkamel, Nima Razzaghi-Asl

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A Versatile Class of 1,4,4-Trisubstituted Piperidines Block Coronavirus Replication In Vitro by Sonia De Castro, Annelies Stevaert, Miguel Maldonado, Adrien Delpal, Julie Vandeput, Benjamin Van Loy, Cecilia Eydoux, Jean-Claude Guillemot, Etienne Decroly, Federico Gago, Bruno Canard, Maria-Jose Camarasa, Sonsoles Velázquez, Lieve Naesens

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A Marine Analgesic Peptide, Contulakin-G, and Neurotensin are Distinct Agonists for Neurotensin Receptors: Uncovering Structural Determinants of Desensitization Properties by Hee-Kyoung eLee, Liuyin eZhang, Misty D Smith, Aleksandra eWalewska, Aleksandra eWalewska, Nadeem eVellore, Riccardo eBaron, J Michael eMcIntosh, H Steve eWhite, Baldomero M Olivera, Grzegorz eBulaj

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New 5-Aryl-1,3,4-Thiadiazole-Based Anticancer Agents: Design, Synthesis, In Vitro Biological Evaluation and In Vivo Radioactive Tracing Studies by Rana M. El-Masry, Basma M. Essa, Adli A. Selim, Soad Z. El-Emam, Khaled O. Mohamed, Tamer M. Sakr, Hanan H. Kadry, Azza T. Taher, Sahar M. Abou-Seri

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Computational evaluation of some compounds as potential anti-breast cancer agents by Momohjimoh Ovaku Idris, Stephen Eyije Abechi, Gideon Adamu Shallangwa

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Biological Profiling of Semisynthetic C19-Functionalized Ferruginol and Sugiol Analogues by Miguel A. González-Cardenete, Fatima Rivas, Rachel Basset, Marco Stadler, Steffen Hering, José M. Padrón, Ramón J. Zaragozá, María Auxiliadora Dea-Ayuela

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In vitro antimicrobial, anticancer evaluation, and in silico studies of mannopyranoside analogs against bacterial and fungal proteins: Acylation leads to improved antimicrobial act... by Md. Ahad Hossain, Shahin Sultana, Mohammed M. Alanazi, Hanine Hadni, Ajmal R. Bhat, Imtiaj Hasan, Sarkar M.A. Kawsar

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Chemoreversal Agents from Taiwanofungus Genus and Their More Potent Methyl Derivatives Targeting Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by Ko-Hua Yu, Chin-Chuan Hung, Tian-Shung Wu, Chin-Fu Chen, I-Ting Wu, Ping-Chung Kuo, Sio-Hong Lam, Hsin-Yi Hung

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A High-Throughput Phenotypic Screen of the 'Pandemic Response Box' Identifies a Quinoline Derivative with Significant Anthelmintic Activity by Harrison T. Shanley, Aya C. Taki, Joseph J. Byrne, Abdul Jabbar, Tim N. C. Wells, Kirandeep Samby, Peter R. Boag, Nghi Nguyen, Brad E. Sleebs, Robin B. Gasser

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