Search Results - "structure–activity relationship"

In vitro clinical trials: the future of cell-based profiling by Nathan T Ross, Christopher J Wilson

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Synthesis of New Opioid Analgesic Peptide Analogues to Enkephalin (Leucine- and Methionine-Enkephalin) by Muthanna S. Al-Ttaee, Kawkab Y. Saour, Ahlam J. Qasir

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Structure-activity exploration of a small-molecule allosteric inhibitor of T790M/L858R double mutant EGFR by Francesca Foschi, Annachiara Tinivella, Valentina Crippa, Luca Pinzi, Luca Mologni, Daniele Passarella, Giulio Rastelli

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Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and IGF-1R by Cornelius Hempel, Frank Totzke, Christoph Schächtele, Abdulkarim Najjar, Wolfgang Sippl, Christoph Ritter, Andreas Hilgeroth

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Design, Synthesis and Biological Evaluation of New 5,5-Diarylhydantoin Derivatives as Selective Cyclooxygenase-2 Inhibitors by Afshin ZARGHI, Farin SATTARY JAVID, Razieh GHODSI, Orkideh G. DADRASS, Bahram DARAEI, Mehdi HEDAYATI

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A Review of Fatty Acid Biosynthesis Enzyme Inhibitors as Promising Antimicrobial Drugs by Laurie Bibens, Jean-Paul Becker, Alexandra Dassonville-Klimpt, Pascal Sonnet

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Kinetic Analysis of High-Temperature Sunflower Oil Peroxidation Inhibited by the Major Families of Phenolic Antioxidants Unveils the Extraordinary Activity of 1,4-Hydroquinones by Fabio Mollica, Lucia Bonoldi, Riccardo Amorati

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Latest advances in dual inhibitors of acetylcholinesterase and monoamine oxidase B against Alzheimer's disease by Dajiang Zou, Renzheng Liu, Yangjing Lv, Jianan Guo, Changjun Zhang, Yuanyuan Xie

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Synthesis and biological evaluation of anti-Toxoplasma gondii activity of a novel scaffold of thiazolidinone derivatives by Simone Carradori, Daniela Secci, Bruna Bizzarri, Paola Chimenti, Celeste De Monte, Paolo Guglielmi, Cristina Campestre, Daniela Rivanera, Claudia Bordón, Lorraine Jones-Brando

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Flavonoids-Macromolecules Interactions in Human Diseases with Focus on Alzheimer, Atherosclerosis and Cancer by Dana Atrahimovich, Dorit Avni, Soliman Khatib

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Consensus docking aid to model the activity of an inhibitor of DNA methyltransferase 1 inspired by de novo design by Diana L. Prado-Romero, Alejandro Gómez-García, Raziel Cedillo-González, Hassan Villegas-Quintero, Juan F. Avellaneda-Tamayo, Edgar López-López, Edgar López-López, Fernanda I. Saldívar-González, Ana L. Chávez-Hernández, José L. Medina-Franco

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The Histone Deacetylase Family: Structural Features and Application of Combined Computational Methods by Antonio Curcio, Roberta Rocca, Stefano Alcaro, Anna Artese

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Design, synthesis, HER2 inhibition and anticancer evaluation of new substituted 1,5-dihydro-4,1-benzoxazepines by Olga Cruz-López, Matilde Ner, Francho Nerín-Fonz, Yaiza Jiménez-Martínez, David Araripe, Juan A. Marchal, Houria Boulaiz, Hugo Gutiérrez-, Joaquín M. Campos, Ana Conejo-García

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Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors by Alessandro Deplano, Mariateresa Cipriano, Federica Moraca, Ettore Novellino, Bruno Catalanotti, Christopher J. Fowler, Valentina Onnis

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Terpenoid natural products exert neuroprotection via the PI3K/Akt pathway by Bingyao Xu, Lan Bai, Lan Bai, Lu Chen, Rongsheng Tong, Rongsheng Tong, Yibin Feng, Jianyou Shi, Jianyou Shi

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Preliminary Cytotoxic Study of Some Novel Furo-2-quinolone Compounds by Nohad A.AlOmari, Adnan O. Omar, Iklas M. Taher

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Indole alkaloid glycosides with a 1'-(phenyl)ethyl unit from Isatis indigotica leaves by Qinglan Guo, Dawei Li, Chengbo Xu, Chenggen Zhu, Ying Guo, Haibo Yu, Xiaoliang Wang, Jiangong Shi

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PK20, a new opioid-neurotensin hybrid peptide that exhibits central and peripheral antinociceptive effects by Tsuda Yuko, Van den Eynde Isabelle, Ballet Steven, Kosson Piotr, Kleczkowska Patrycja, Tourwé Dirk, Lipkowski Andrzej W

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Inhibitors of histone deacetylase 6 based on a novel 3-hydroxy-isoxazole zinc binding group by Pasquale Linciano, Luca Pinzi, Silvia Belluti, Ugo Chianese, Rosaria Benedetti, Davide Moi, Lucia Altucci, Silvia Franchini, Carol Imbriano, Claudia Sorbi, Giulio Rastelli

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Computational Drug Repurposing for Antituberculosis Therapy: Discovery of Multi-Strain Inhibitors by Valeria V. Kleandrova, Marcus T. Scotti, Alejandro Speck-Planche

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