Search Results - "structure–activity relationship"

QSAR Study of Anthranilic Acid Sulfonamides as Inhibitors of Methionine Aminopeptidase-2 using different chemometrics tools by Pooria Zare, Maryam Sabet, Razieh Sabet

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Design, Synthesis and Biological Evaluation of Aromatase Inhibitors Based on Sulfonates and Sulfonamides of Resveratrol by Marialuigia Fantacuzzi, Marialucia Gallorini, Nicola Gambacorta, Alessandra Ammazzalorso, Zeineb Aturki, Marwa Balaha, Simone Carradori, Letizia Giampietro, Cristina Maccallini, Amelia Cataldi, Orazio Nicolotti, Rosa Amoroso, Barbara De Filippis

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Preliminary Cytotoxic Study of Some Novel Furo-2-quinolone Compounds by Nohad A.AlOmari, Adnan O. Omar, Iklas M. Taher

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Cationic Surfactants Based on Arginine-Phenylalanine and Arginine-Tryptophan: Synthesis, Aggregation Behavior, Antimicrobial Activity, and Biodegradation by Lourdes Pérez, María Teresa García, Aurora Pinazo, Edgar Pérez-Matas, Zakaria Hafidi, Elena Bautista

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Design, synthesis and evaluation of dihydro-1H-indene derivatives as novel tubulin polymerisation inhibitors with anti-angiogenic and antitumor potency by Shengtao Xu, Yijun Sun, Peng Wang, Yuchen Tan, Lei Shi, Jian Chen

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Design, synthesis and biological evaluation of novel triazoloquinazolinone and imidazoquinazolinone derivatives as allosteric inhibitors of SHP2 phosphatase by Wenjun Ye, Ye Liu, Qian Ren, Tianhui Liao, Yumei Chen, Dongmei Chen, Sisi Wang, Lihong Yao, Yihe Jia, Chunshen Zhao, Zhixu Zhou

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Design, synthesis, and evaluation of novel stilbene derivatives that degrade acidic nucleoplasmic DNA-binding protein 1 (And1) and synergize with PARP1 inhibitor in NSCLC cells by Leyuan Chen, Zhonghao Ren, Yunze Zhang, Wenbin Hou, Yiliang Li

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Novel Non-Congeneric Derivatives of the Choline Kinase Alpha Inhibitor ICL-CCIC-0019 by Ning Wang, Diana Brickute, Marta Braga, Chris Barnes, Haonan Lu, Louis Allott, Eric O. Aboagye

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QSAR Studies, Synthesis, and Biological Evaluation of New Pyrimido-Isoquinolin-Quinone Derivatives against Methicillin-Resistant <i>Staphylococcus aureus</i> by Juan Andrades-Lagos, Javier Campanini-Salinas, Gianfranco Sabadini, Victor Andrade, Jaime Mella, David Vásquez-Velásquez

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Synthesis, telomerase inhibitory and anticancer activity of new 2-phenyl-4H-chromone derivatives containing 1,3,4-oxadiazole moiety by Xu Han, Yun Long Yu, Duo Ma, Zhao Yan Zhang, Xin Hua Liu

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Antimicrobial and Cytotoxic Effects of Cannabinoids: An Updated Review with Future Perspectives and Current Challenges by Mansab Ali Saleemi, Noorfatimah Yahaya, Nur Nadhirah Mohamad Zain, Muggundha Raoov, Yoke Keong Yong, Nurul Shahfiza Noor, Vuanghao Lim

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Characterization of the depsidone gene cluster reveals etherification, decarboxylation and multiple halogenations as tailoring steps in depsidone assembly by Jiafan Yang, Zhenbin Zhou, Yingying Chen, Yongxiang Song, Jianhua Ju

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Chemistry-led investigations into the mode of action of NAMPT activators, resulting in the discovery of non-pyridyl class NAMPT activators by Siyuan Tang, Miguel Garzon Sanz, Oliver Smith, Andreas Krämer, Daniel Egbase, Paul W. Caton, Stefan Knapp, Sam Butterworth

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Molecular determinant deciphering of MIC-guided RND efflux substrates in E. coli by Johan Revol-Tissot, Johan Revol-Tissot, Gérard Boyer, Sandrine Alibert

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New Acyl Derivatives of 3-Aminofurazanes and Their Antiplasmodial Activities by Theresa Hermann, Patrick Hochegger, Johanna Dolensky, Werner Seebacher, Robert Saf, Marcel Kaiser, Pascal Mäser, Robert Weis

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Chemical Constituents and Their Biological Activities from Genus <i>Styrax</i> by Ding-Ding Xia, Xin-Yu Han, Yu Zhang, Na Zhang

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Structure-based design, synthesis, and biological evaluation of novel pyrimidinone derivatives as PDE9 inhibitors by Xu-Nian Wu, Ya-Dan Huang, Jin-Xuan Li, Yan-Fa Yu, Zhou Qian, Chen Zhang, Yinuo Wu, Hai-Bin Luo

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Molecular Design, Synthesis and Trypanocidal Activity of Dipeptidyl Nitriles as Cruzain Inhibitors. by Leandro A A Avelar, Cristian D Camilo, Sérgio de Albuquerque, William B Fernandes, Cristiana Gonçalez, Peter W Kenny, Andrei Leitão, James H McKerrow, Carlos A Montanari, Erika V Meñaca Orozco, Jean F R Ribeiro, Josmar R Rocha, Fabiana Rosini, Marta E Saidel

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Update on the Discovery of Efflux Pump Inhibitors against Critical Priority Gram-Negative Bacteria by Nina Compagne, Anais Vieira Da Cruz, Reinke T. Müller, Ruben C. Hartkoorn, Marion Flipo, Klaas M. Pos

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Methoxy and bromo scans on N-(5-methoxyphenyl) methoxybenzenesulphonamides reveal potent cytotoxic compounds, especially against the human breast adenocarcinoma MCF7 cell line by Myriam González, María Ovejero-Sánchez, Alba Vicente-Blázquez, Manuel Medarde, Rogelio González-Sarmiento, Rafael Peláez

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