Search Results - "translational science"

The estimation and translation uncertainties in applying NOAEL to clinical dose escalation by Chao Chen, Silvia Maria Lavezzi, David McDougall

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Early Adalimumab and Anti‐Adalimumab Antibody Levels for Prediction of Primary Nonresponse in Ankylosing Spondylitis Patients by Xiaoliang Ding, Ruifang Zhu, Jian Wu, Ling Xue, Meihua Gu, Liyan Miao

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Pharmacokinetics of biologics in gastric cancer by Junyi Li, David C. Turner, Feifei Li, Xi Chen, Michael Z. Liao, Chunze Li

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Gossypol improves myocardial dysfunction caused by sepsis by regulating histone acetylation by Xiaohui Shi, Xinwei Lv, Dong Xiao

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Safety and pharmacokinetics of docetaxel in combination with pegvorhyaluronidase alfa in patients with non‐small cell lung cancer by Thomas Heineman, Megan Baumgart, Charvi Nanavati, Nash Gabrail, Scott A. Van Wart, Donald E. Mager, Daniel C. Maneval, Anas M. Fathallah, Rose E. Sekulovich

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Recent advances and clinical pharmacology aspects of Chimeric Antigen Receptor (CAR) T‐cellular therapy development by Johannes Kast, Saeideh Nozohouri, Di Zhou, Marc R. Yago, Po‐Wei Chen, Malidi Ahamadi, Sandeep Dutta, Vijay V. Upreti

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Optimizing a therapy for opiate use disorders: Characterizing ondansetron pharmacokinetics in blood and brain by Manhong Wu, Zhuanfen Cheng, Anthony T. Le, Yalun Tan, Gary Peltz

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Development and Validation of a Risk Prediction Model of Vancomycin‐Associated Nephrotoxicity in Elderly Patients: A Pilot Study by Chen Pan, Aiping Wen, Xingang Li, Dandan Li, Yang Zhang, Yin Liao, Yue Ren, Su Shen

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Alternative Splicing of the SLCO1B1 Gene: An Exploratory Analysis of Isoform Diversity in Pediatric Liver by Bianca D. vanGroen, Chengpeng Bi, Roger Gaedigk, Vincent S. Staggs, Dick Tibboel, Saskia N. deWildt, J. Steven Leeder

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Characterization of the Relationship of Inotuzumab Ozogamicin Exposure With Efficacy and Safety End Points in Adults With Relapsed or Refractory Acute Lymphoblastic Leukemia by Joseph Chen, May Haughey, Erik Vandendries, Daniel J. DeAngelo, Hagop M. Kantarjian, Ana Ruiz‐Garcia

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Evaluation of potential drug-drug interactions with medical cannabis by Jessie Jia Yi Ho, Chenyi Goh, Caitlin Shen Ai Leong, Khuen Yen Ng, Athirah Bakhtiar

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Pharmacogenetics in Practice: Estimating the Clinical Actionability of Pharmacogenetic Testing in Perioperative and Ambulatory Settings by D. Max Smith, Beth N. Peshkin, T. Blaise Springfield, Ryan P. Brown, Elizabeth Hwang, Susanna Kmiecik, Richard Shapiro, Zayd Eldadah, Conor Lundergan, Joel McAlduff, Bonnie Levin, Sandra M. Swain

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The Weight of Evidence From Electrophysiology, Observational, and Cardiovascular End Point Studies Demonstrates the Safety of Azithromycin by Jack Cook, Milton L. Pressler, Bharat Damle, Demissie Alemayehu, Charles A. Knirsch

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The expanding universe of NUTM1 fusions in pediatric cancer by Rosane Charlab, Rebecca Racz

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Is there a possibility that P‐glycoprotein reduces reproductive toxicity in males but breast cancer resistance protein does not? by Zhiheng Yu, Wei Liu, Ziyu Wang, Yidong Chen, Jie Yan, Leslie Z. Benet, Suodi Zhai

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Reduction of Renal Preservation/Reperfusion Injury by Controlled Hyperthermia During Ex Vivo Machine Perfusion by Thomas Minor, Charlotte vonHorn

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Lipid droplet screen in human hepatocytes identifies TRRAP as a regulator of cellular triglyceride metabolism by Deepti Abbey, Donna Conlon, Christopher Rainville, Susannah Elwyn, Katherine Quiroz‐Figueroa, Jeffrey Billheimer, David C. Schultz, Nicholas J. Hand, Sara Cherry, Daniel J. Rader

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Factors Associated with Eczema Clinical Trial Awareness, Interest, and Participation in Adults by Erin E. Grinich, Isabelle J. Thibau, Emile Latour, Kyla N. Price, Allison R. Loiselle, Eric Simpson, Wendy Smith Begolka

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Trends in oncology drug lags in Japan from 2001 to 2020: A cross‐sectional study by Hideki Maeda, Asuka Hara, Momoka Ofuchi, Riko Shingai, Toshihiro Misumi, Yuna Murai

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Non‐alkylating agents‐induced gonadotoxicity in pre‐pubertal males: Insights on the clinical and pre‐clinical front by Sruthi Sriram, Tiago Macedo, Annelies Mavinkurve‐Groothuis, Marianne van deWetering, Leendert H. J. Looijenga

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