Search Results - "translational science"

A "one‐step" approach to heart rate correction and statistical analysis applied to conscious dog QTc studies by Derek D. Best, Matthew M. Abernathy, Derek J. Leishman

Connect to this object online.

Adapting regulatory drug‐drug interaction guidance to design clinical pharmacokinetic natural product‐drug interaction studies: A NaPDI Center recommended approach by Emily J. Cox, Allan E. Rettie, Jashvant D. Unadkat, Kenneth E. Thummel, Jeannine S. McCune, Mary F. Paine

Connect to this object online.

Pharmacogenetic variants of infliximab response in young patients with inflammatory bowel disease by Debora Curci, Marianna Lucafò, Adriana Cifù, Martina Fabris, Matteo Bramuzzo, Stefano Martelossi, Raffaella Franca, Giuliana Decorti, Gabriele Stocco

Connect to this object online.

Rivaroxaban Precision Dosing Strategy for Real‐World Atrial Fibrillation Patients by Robyn Konicki, Daniel Weiner, J. Herbert Patterson, Daniel Gonzalez, Angela Kashuba, Yanguang Carter Cao, Anil K. Gehi, Paul Watkins, J. Robert Powell

Connect to this object online.

What men want: Results from a national survey on decision making for prostate cancer treatment and research participation by Nancy P. Mendenhall, Sarah M. Rausch Osian, Curtis M. Bryant, Bradford S. Hoppe, Christopher G. Morris

Connect to this object online.

A pilot study to identify pharmacogenomic and clinical risk factors associated with opioid related falls and adverse effects in older adults by Sophia Sheikh, Rosemarie Fernandez, Carmen Smotherman, Jennifer Brailsford, Taimour Langaee, Esteban Velasquez, Morgan Henson, Taylor Munson, Andrew Bertrand, Phyllis Hendry, Stephen Anton, Roger B. Fillingim, Larisa H. Cavallari

Connect to this object online.

Comparison of Efficacy of Dipeptidyl Peptidase‐4 Inhibitors and Sodium‐Glucose Co‐Transporter 2 Inhibitors Between Japanese and Non‐Japanese Patients: A Meta‐Analysis by Yuka Ito, Kaori Ambe, Toshiki Hayase, Mayu Kobayashi, Masahiro Tohkin

Connect to this object online.

Exposure-Response Modeling and Simulation of Progression‐Free Survival and Adverse Events of Sorafenib Treatment in Patients With Advanced Thyroid Cancer by Joachim Grevel, Garrit Jentsch, Rupert Austin, Nicolaas H. Prins, John Lettieri, David Mitchell, Funan Huang, Marcia S. Brose, Martin Schlumberger, Gerold Meinhardt, Carol E. A. Peña, Bart A. Ploeger

Connect to this object online.

Real‐Time and Wireless Assessment of Adherence to Antiretroviral Therapy With Co‐Encapsulated Ingestion Sensor in HIV‐Infected Patients: A Pilot Study by Eric S. Daar, Marc I. Rosen, Yan Wang, Lisa Siqueiros, Jie Shen, Mario Guerrero, Di Xiong, John Dao, Todd Young, Katya Corado, Courtney V. Fletcher, Honghu Liu

Connect to this object online.

The Labyrinth of Product Development and Regulatory Approvals in Liquid Biopsy Diagnostics by Federico M. Goodsaid

Connect to this object online.

Pharmacokinetics of bempedoic acid in patients with renal impairment by Benny M. Amore, William J. Sasiela, Daniel K. Ries, Perry Tresh, Maurice G. Emery

Connect to this object online.

uConsent: Addressing the gap in measuring understanding of informed consent in clinical research by Richard F. Ittenbach, J. William Gaynor, Jenny M. Dorich, Nancy B. Burnham, Guixia Huang, Madisen T. Harvey, Jeremy J. Corsmo

Connect to this object online.

Accelerating vaccine trial conduct in a pandemic with a hot spot‐based inclusion strategy using trial and epidemic simulation by Johan L. van derPlas, Michiel J. vanEsdonk, Ingrid M. C. Kamerling, Adam F. Cohen

Connect to this object online.

Physiologically based modeling reveals different risk of respiratory depression after fentanyl overdose between adults and children by Shilpa Chakravartula, Bradlee Thrasher, John Mann, Anik Chaturbedi, Xiaomei Han, Albert Dahan, Jeffry Florian, David Strauss, Zhihua Li

Connect to this object online.

Lipidomics of cyclophosphamide 4‐hydroxylation in patients receiving post‐transplant cyclophosphamide by Sandi L. Navarro, Zihan Zheng, Timothy W. Randolph, Ryotaro Nakamura, Brenda M. Sandmaier, David Hockenbery, Jeannine S. McCune

Connect to this object online.

Pharmacogenomics polygenic risk score: Ready or not for prime time? by Sonal Singh, Gabriele Stocco, Katherine N. Theken, Alyson Dickson, QiPing Feng, Jason H. Karnes, Jonathan D. Mosley, Nihal El Rouby

Connect to this object online.

Influence of CYP2D6 metabolizer status on ondansetron efficacy in pediatric patients undergoing hematopoietic stem cell transplantation: A case series by Andrea Edwards, Ashley Teusink‐Cross, Lisa J. Martin, Cynthia A. Prows, Parinda A. Mehta, Laura B. Ramsey

Connect to this object online.

Population pharmacokinetics and exposure‐response analyses for efficacy and safety of upadacitinib in patients with axial spondyloarthritis by Sumit Bhatnagar, Doerthe Eckert, Sven Stodtmann, In‐Ho Song, Peter Wung, Wei Liu, Mohamed‐Eslam F. Mohamed

Connect to this object online.

Bioequivalence study of dacomitinib and Vizimpro® in healthy Chinese volunteers under fasting and fed conditions: A randomized, open‐label, single‐dose, crossover trial by Xiaojia Yang, Jinfang Li, Taihui Zhang, Qinping Xia, Wei Zhang, Yike Cui, Wen He

Connect to this object online.

Expert survey on real‐world data utilization and real‐world evidence generation for regulatory decision‐making in drug lifecycle in Korea by Hankil Lee, Hyeon‐Soo Ahn, Sol Kwon, Hye‐Young Kang, Euna Han

Connect to this object online.