Search Results - "translational science"

Sources of pharmacokinetic and pharmacodynamic variability and clinical pharmacology studies of antiseizure medications in the pediatric population by Patricia D. Maglalang, Jiali Wen, Christoph P. Hornik, Daniel Gonzalez

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Implementing pain, agitation, delirium, and sleep deprivation protocol in critically ill patients: A pilot study on pharmacological interventions by Punchika Luetrakool, Suthinee Taesotikul, Kanyarat Susantitapong, Chuthamanee Suthisisang, Sunthiti Morakul, Yuda Sutherasan, Viratch Tangsujaritvijit, Pitchaya Dilokpattanamongkol

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Associations of cold‐inducible RNA‐binding protein with bacterial load, proinflammatory cytokines and mortality from pneumonia by Qi Guo, Hai‐yan Li, Chao Zeng, Zhong‐dong Lü, Mei Jiang

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Mechanistic Multiscale Pharmacokinetic Model for the Anticancer Drug 2',2'‐difluorodeoxycytidine (Gemcitabine) in Pancreatic Cancer by Maria Garcia‐Cremades, Nicola Melillo, Iñaki F. Troconiz, Paolo Magni

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Safety, pharmacokinetics, and pharmacodynamics of ART‐648, a PDE4 inhibitor in healthy subjects: A randomized, placebo‐controlled phase I study by Akira Tanaka, Hiroshi Nagabukuro, Kanako Kuniyeda, Haruhi Ando, Toshinori Higashi, Hirokazu Wakuda, Naoyuki Otani, Hideo Kudo, Masae Kuranari, Hidetoshi Furuie, Naoto Uemura

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A review of clinical efficacy data supporting emergency use authorization for COVID‐19 therapeutics and lessons for future pandemics by Seo‐Hyun Yoo, Lauren Kim, Michelle Lu, Kira Nagoshi, Mark N. Namchuk

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Pharmacokinetics of Favipiravir in Critically Ill Patients With COVID‐19 by Kei Irie, Atsushi Nakagawa, Hirotoshi Fujita, Ryo Tamura, Masaaki Eto, Hiroaki Ikesue, Nobuyuki Muroi, Keisuke Tomii, Tohru Hashida

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Empowering drug development: Leveraging insights from imaging technologies to enable the advancement of digital health technologies by Elena S. Izmailova, R. Paul Maguire, Timothy J. McCarthy, Martijn L. T. M. Müller, Philip Murphy, Diane Stephenson

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Evaluation of the potential complication of interstitial lung disease associated with antifibrotic drugs using data from databases reporting spontaneous adverse effects by Hideki Nawa, Hirofumi Hamano, Takahiro Niimura, Koji Miyata, Kenta Yagi, Mitsuhiro Goda, Yoshito Zamami, Keisuke Ishizawa

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The impact of skin color and tone on histamine iontophoresis and Doppler flowmetry measurements as a pharmacodynamic biomarker by Aarya Ramprasad, Adara Ezekwe, Brian R. Lee, Shiva Balasubramanian, Bridgette L. Jones

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Clinical characteristics in early Parkinson's disease with excessive daytime sleepiness: A cross‐sectional and longitudinal study by Yumei Liu, Ling Xue, Jun Zhao, Kaixin Dou, Guojun Wang, Anmu Xie

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Population pharmacokinetic modeling and simulations of berotralstat for prophylactic treatment of attacks of hereditary angioedema by Amanda Mathis, Mark Sale, Melanie Cornpropst, William P. Sheridan, Shu Chin Ma

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Perceptions of pharmacogenetic exceptionalism and the implications for clinical management within an electronic health record by Tiana Butler, Jacob Brown, Pamala A. Jacobson, David Stenehjem

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Mechanistic Modeling of Intra‐Tumor Spatial Distribution of Antibody‐Drug Conjugates: Insights into Dosing Strategies in Oncology by Jared Weddell, Manoj S. Chiney, Sumit Bhatnagar, John P. Gibbs, Mohamad Shebley

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Bone marrow mesenchymal stromal cells support regeneration of intestinal damage in a colitis mouse model, independent of their CXCR4 expression by Burcu Pervin, Merve Gizer, Mehmet Emin Şeker, Özgür Doğuş Erol, Sema Nur Gür, Ece Gizem Polat, Bahar Değirmenci, Petek Korkusuz, Fatima Aerts‐Kaya

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Potential benefit of vitamin D supplementation in people with respiratory illnesses, during the COVID‐19 pandemic by Vasudevan V. Chetty, Manoranjenni Chetty

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Pioglitazone‐induced alterations of purine metabolism in healthy male subjects by Jihyun Kang, Yufei Li, SeungHwan Lee, Kyung‐Sang Yu, Joo‐Youn Cho

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A novel analytical framework for risk stratification of real‐world data using machine learning: A small cell lung cancer study by Luca Marzano, Adam S. Darwich, Salomon Tendler, Asaf Dan, Rolf Lewensohn, Luigi De Petris, Jayanth Raghothama, Sebastiaan Meijer

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EDP‐297: A novel, farnesoid X receptor agonist-Results of a phase I study in healthy subjects by Christine Marotta, Alaa Ahmad, Ed Luo, Jart Oosterhaven, Sjoerd vanMarle, Nathalie Adda

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Effect of Genetic and Nongenetic Factors on the Clinical Response to Mineralocorticoid Receptor Antagonist Therapy in Egyptians with Heart Failure by Neven M. Sarhan, Mohamed H. Shahin, Nihal M. El Rouby, Lamia M. El‐Wakeel, Mohamed H. Solayman, Taimour Langaee, Hazem Khorshid, Mona F. Schaalan, Nagwa A. Sabri, Larisa H. Cavallari

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