Search Results - "translational science"

MVP enhances FGF21‐induced ferroptosis in hepatocellular carcinoma by increasing lipid peroxidation through regulation of NOX4 by Jinkun Xia, Boqi Fu, Zhe Wang, Gaolin Wen, Quanshui Gu, Dayu Chen, Haozhen Ren

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Chasing the storm: Recruiting non‐hospitalized patients for a multi‐site randomized controlled trial in the United States during the COVID‐19 pandemic by Kelly Hu, Jean‐Claude Tardif, Melanie Huber, Maria Daly, Aisha T. Langford, Ruth Kirby, Yves Rosenberg, Judith Hochman, Avni Joshi, Zohar Bassevitch, Michael H. Pillinger, Binita Shah

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Omiganan Enhances Imiquimod‐Induced Inflammatory Responses in Skin of Healthy Volunteers by Tessa Niemeyer‐van der Kolk, Salma Assil, Thomas P. Buters, Melanie Rijsbergen, Erica S. Klaassen, Gary Feiss, Edwin Florencia, Errol P. Prens, Jacobus Burggraaf, Martijn B.A. vanDoorn, Robert Rissmann, Matthijs Moerland

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Outcomes of intermediate or high‐risk CMML patients treated with hypomethylating agents combined with venetoclax: A single center experience by Chao Li, ChengXin Deng, Ping Wu, KaiFan Liu, Xin Huang, MingMin Li, XiaoMei Chen, SuXia Geng, PeiLong Lai, JianYu Weng, Xin Du

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A randomized, double‐blind, placebo‐ and positive‐controlled crossover study of the effects of durlobactam on cardiac repolarization in healthy subjects by John O'Donnell, Kathleen Maloney, Melissa Steidler, Royce Morrison, Robin Isaacs

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Pharmacokinetics of single‐dose rivaroxaban under fed state in obese vs. non‐obese subjects: An open‐label controlled clinical trial (RIVOBESE‐PK) by Majdoleen Alalawneh, Ahmed Awaisu, Ibtihal Abdallah, Hazem Elewa, Mohammed Danjuma, Kamal M. Matar, Akram M. ElKashlan, Yasser Elshayep, Fathy Ibrahim, Ousama Rachid

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Tumor biomarkers in evaluating the severity and prognosis of idiopathic pulmonary arterial hypertension: A comprehensive analysis by Xin Li, Yi Zhang, Sicheng Zhang, Qing Zhao, Qi Jin, Anqi Duan, Zhihua Huang, Luyang Gao, Yijia Wang, Sicong Li, Zhihui Zhao, Qin Luo, Zhihong Liu

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Expression pattern of osteopontin isoforms in malignant melanoma cell lines by Viktoria Koroknai, István Szász, Krisztina Jámbor, Margit Balázs

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Identification and Evaluation of Clinical Substrates of Organic Anion Transporting Polypeptides 1B1 and 1B3 by Savannah J. McFeely, Tasha K. Ritchie, Jingjing Yu, Anna Nordmark, René H. Levy, Isabelle Ragueneau‐Majlessi

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Estimation of Body Fat Percentage for Clinical Pharmacokinetic Studies in Children by Thomas P. Green, Helen J. Binns, Huali Wu, Adolfo J. Ariza, Eliana M. Perrin, Maheen Quadri, Christoph P. Hornik, Michael Cohen‐Wolkowiez

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Predicting In Vivo Efficacy from In Vitro Data: Quantitative Systems Pharmacology Modeling for an Epigenetic Modifier Drug in Cancer by Mehdi Bouhaddou, Li J. Yu, Serena Lunardi, Spyros K. Stamatelos, Fiona Mack, James M. Gallo, Marc R. Birtwistle, Antje‐Christine Walz

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Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: A Pharmacokinetic, Microbiome, and Untargeted Metabolomics Study by Alan K. Jarmusch, Alison Vrbanac, Jeremiah D. Momper, Joseph D. Ma, Maher Alhaja, Marlon Liyanage, Rob Knight, Pieter C. Dorrestein, Shirley M. Tsunoda

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Adult and pediatric relapsing multiple sclerosis phase II and phase III trial design and their primary end points: A systematic review by Katsutoshi Hiramatsu, Hideki Maeda

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Preclinical metabolism and metabolic drug-drug interaction profile of pedunculoside and rotundic acid by Liang Wu, Linling Dong, Zhu Zhou, Xin Wang, Yujie Lin, Xuesong Shi, Peijing Wang, Suocheng Xu, Zhiyi Fang

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A cross‐sectional survey on principal investigators' clinical research knowledge in Japan by Miwa Sekine, Koshi Kataoka, Yuji Nishizaki, Kotone Matsuyama, Toshiaki Otsuka, Kensuke Sato, Mayumi Idei, Shoji Sanada

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Safety, tolerability, and pharmacokinetics of oral baicalein tablets in healthy Chinese subjects: A single‐center, randomized, double‐blind, placebo‐controlled multiple‐ascending‐d... by Lijun Li, Hongzhi Gao, Kun Lou, Hongmei Luo, Sheng Hao, Jing Yuan, Zeyuan Liu, Ruihua Dong

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Questions in self‐selection studies used in consumer research for nonprescription drug candidates: Limitations and recommendations by Eric P. Brass, Russell D. Bradford, Arthur Stone

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Evaluation of atezolizumab immunogenicity: Efficacy and safety (Part 2) by Solange Peters, Peter R. Galle, Coen A. Bernaards, Marcus Ballinger, René Bruno, Valerie Quarmby, Jane Ruppel, Alexandr Vilimovskij, Benjamin Wu, Nitzan Sternheim, Martin Reck

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Going beyond bibliometrics: A system to track the progress and impact of biomedical research funded by Susan G. Komen by Amy M. Dworkin, Stephanie Reffey, Kari Wojtanik

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Precision medicine in Asia enhanced by next‐generation sequencing: Implications for Thailand through a scoping review and interview study by Chumut Phanthunane, Sutatip Pongcharoen, Supasit Pannarunothai, Jureepon Roboon, Pudtan Phanthunane, Jiraluck Nontarak

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