Search Results - "translational science"

Launching a multidisciplinary European collaboration towards a cure for HIV: The EU2Cure Consortium by C. Rokx, H.A.B. Prins, L. Vandekerckhove, S.J. Fidler, J. Frater, M. Bracchi, O.S. Søgaard, M. Tolstrop, T.A. Rasmussen, M. Salgado, J. Blanco, J. Martinez-Picado, B. Clotet, G. Tambussi, A. Groenendijk, A. Verbon, C.A.B. Boucher

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Investigation of the anticancer mechanism of monensin via apoptosis‐related factors in SH‐SY5Y neuroblastoma cells by Sema Serter Kocoglu, Ceren Oy, Mücahit Secme, F. Bahar Sunay

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Public Interest in Medical Research Participation: Differences by Volunteer Status and Study Type by Enesha M. Cobb, Dianne C. Singer, Matthew M. Davis

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Influence of CYP2D6 genetic variation on adverse events with propafenone in the pediatric and young adult population by Sudeep D. Sunthankar, Prince J. Kannankeril, Andrea Gaedigk, Andrew E. Radbill, Frank A. Fish, Sara L. Van Driest

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DNA Methylation‐Based Epigenetic Repression of SLC22A4 Promotes Resistance to Cytarabine in Acute Myeloid Leukemia by Daelynn R. Buelow, Jason T. Anderson, Stanley B. Pounds, Lei Shi, Jatinder K. Lamba, Shuiying Hu, Alice A. Gibson, Emily A. Goodwin, Alex Sparreboom, Sharyn D. Baker

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Re‐discover the value of protein binding assessments in hepatic and renal impairment studies and its contributions in drug labels and dose decisions by Jocelyn Courville, Kathryn Roupe, Gerhard Arold

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Modeling the subcutaneous pharmacokinetics of antibodies co‐administered with rHuPH20 by Ryan P. Nolan, Marie A. Printz

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Effect of Repeated Intravenous Amantadine Infusions in Patients with Parkinson's Disease: An Open‐Label Pilot Study by Alexander Khlebtovsky, Israel Steiner, Therese Treves, Ruth Djaldetti

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Time‐dependent clearance can confound exposure-response analysis of therapeutic antibodies: A comprehensive review of the current literature by Jeffrey R. Proctor, Harvey Wong

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Required dose of sugammadex or neostigmine for reversal of vecuronium‐induced shallow residual neuromuscular block at a train‐of‐four ratio of 0.3 by Jing He, Huan He, Xing Li, Mei Sun, Zhihao Lai, Bo Xu

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Integrating real‐world data and machine learning: A framework to assess covariate importance in real‐world use of alternative intravenous dosing regimens for atezolizumab by Bianca Vora, Ashutosh Jindal, Erick Velasquez, James Lu, Benjamin Wu

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Nrf‐2/ROS/NF‐κB pathway is modulated by cynarin in human mesenchymal stem cells in vitro from ankylosing spondylitis by Chenyu Song, Kaiyang Wang, Bangping Qian, Jingshun Lu, Mu Qiao, Yong Qiu, Bin Wang, Yang Yu

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Factors related to polypharmacy and hyper‐polypharmacy for the elderly: A nationwide cohort study using National Health Insurance data in South Korea by Ho Jin Cho, Jungmi Chae, Sang‐Heon Yoon, Dong‐Sook Kim

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Approval success rates of drug candidates based on target, action, modality, application, and their combinations by Shingo Yamaguchi, Masayuki Kaneko, Mamoru Narukawa

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Data Management 101 for drug developers: A peek behind the curtain by Bryan Oronsky, Erica Burbano, Meaghan Stirn, Joanne Brechlin, Nacer Abrouk, Scott Caroen, Angelique Coyle, Jeannie Williams, Pedro Cabrales, Tony R. Reid

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Pediatric CYP2D6 metabolizer status and post‐tonsillectomy nausea and vomiting after ondansetron by Katherine Black, B. Randall Brenn, Andrea Gaedigk, Jonathan P. Wanderer, Sara L. Van Driest

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Increased serum amiodarone concentration in hypertriglyceridemic patients: Effects of drug distribution to serum lipoproteins by Naoaki Hashimoto, Kosuke Doki, Satoru Kawano, Kazutaka Aonuma, Masaki Ieda, Masato Homma

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In Vitro‐to‐In Vivo Extrapolation of Transporter Inhibition Data for Drugs Approved by the US Food and Drug Administration in 2018 by Jingjing Yu, Isabelle Ragueneau‐Majlessi

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Proteomic study on the lymphocytes from pregnant Wistar rat females treated with immunosuppressive regimen by Bartosz Wojciuk, Aleksandra Bogucka, Paulina Czaplewska, Patrycja Okulewicz, Iwona Wojciechowska‐Koszko, Kazimierz Ciechanowski, Joanna Kabat‐Koperska

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Translational researchers' training and development needs, preferences, and barriers: A survey in a National Institute for Health Research Biomedical Research Centre in the United... by Karen Bell, Syed Ghulam Sarwar Shah, Lorna R. Henderson, Vasiliki Kiparoglou

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