Search Results - "translational science"

The Translational Approaches to Personalized Health Collaborative: Pharmacogenomics for African American Older Adults by Lana JSargent, Marissa Mackiewicz, Youssef Roman, Ana Diallo, Sally Russell, Katherine Falls, Kristin M. Zimmerman, Dave L. Dixon, Elizabeth Prom‐Wormley, Sarah Hobgood, Sarah K. Lageman, Faika Zanjani, Elvin T. Price

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Optimized fosfomycin regimens for treating carbapenem‐resistant Acinetobacter baumannii in critically ill patients with varying degrees of renal function by Nattapong Tidwong, Anan Chanruang, Suthanya Chupradit, Suzanne L. Parker, Pannee Leelawattanachai, Poramed Winichakoon, Baralee Punyawudho

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A Practice‐Based, Clinical Pharmacokinetic Study to Inform Levetiracetam Dosing in Critically Ill Patients Undergoing Continuous Venovenous Hemofiltration (PADRE‐01) by Shamir N. Kalaria, Michael Armahizer, Paul McCarthy, Neeraj Badjatia, Jogarao V. Gobburu, Mathangi Gopalakrishnan

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Tutorial: Statistical analysis and reporting of clinical pharmacokinetic studies by Ann‐Cathrine Dalgård Dunvald, Ditte Bork Iversen, Andreas Ludvig Ohm Svendsen, Katrine Agergaard, Ida Berglund Kuhlmann, Christina Mortensen, Nanna Elman Andersen, Erkka Järvinen, Tore Bjerregaard Stage

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Digitally Enabled, Patient‐Centric Clinical Trials: Shifting the Drug Development Paradigm by Marissa F. Dockendorf, Bryan J. Hansen, Kevin P. Bateman, Matthew Moyer, Jyoti K. Shah, Lisa A. Shipley

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Benchmarking pharmacogenomics genotyping tools: Performance analysis on short‐read sequencing samples and depth‐dependent evaluation by Andreas Halman, Sebastian Lunke, Simon Sadedin, Claire Moore, Rachel Conyers

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Pharmacokinetics and safety of a novel influenza treatment (baloxavir marboxil) in Korean subjects compared with Japanese subjects by Yun Kim, Sangwon Lee, Yohan Kim, In‐Jin Jang, SeungHwan Lee

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Abemaciclib does not increase the corrected QT interval in healthy participants by Jill C. Chappell, Alan Y. Chiang, Jane Royalty, Hugh Coleman, Palaniappan Kulanthaivel, P. Kellie Turner

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Overview of the Premarketing and Postmarketing Requirements for Drugs Granted Japanese Conditional Marketing Approval by Shunsuke Matsushita, Keisuke Tachibana, Tetsuya Kusakabe, Ryuichi Hirayama, Yasuo Tsutsumi, Masuo Kondoh

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The Relationship Between the Level of Serum ESM‐1 and Lp‐PLA2 in Patients With Acute ST‐Segment Elevation Myocardial Infarction by Peng Wei, Bin Zong, Xuekui Liu, Miaomiao Zhang, Cui Yang, Haibo Wang, Qiang Fu, Liansheng Wang, Bangming Cao

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Variational autoencoders for generative modeling of drug dosing determinants in renal, hepatic, metabolic, and cardiac disease states by Raginee R. Titar, Murali Ramanathan

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Leveraging large observational studies to discover genetic determinants of drug concentrations: A proof‐of‐concept study by Maxime Meloche, Grégoire Leclair, Martin Jutras, Essaïd Oussaïd, Marie‐Josée Gaulin, Ian Mongrain, David Busseuil, Jean‐Claude Tardif, Marie‐Pierre Dubé, Simon deDenus

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Early administration of ketorolac after cardiac surgery and postoperative complications: Analysis of the MIMIC‐IV database by Yi Liu, Bo Pan, Jie Liu, Jun Zhang

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Modeling and simulation to predict the degree of disability over time in acute ischemic stroke patients by Sang‐In Park, Dong‐Wha Kang, Hyeong‐Seok Lim

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Pharmacokinetics, pharmacodynamics, and safety of frunexian in healthy Chinese volunteer adults: A randomized dose‐escalation phase I study by Jia‐yu Zhang, Zou‐rong Ruan, Bo Jiang, Dan‐dan Yang, Jia‐ying Wang, Yin Hu, Yong‐rui Wang, Yan‐mei Wang, Yun‐fei Lin, Ling‐ling Wang, Hong‐gang Lou

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A public-private collaboration model for clinical innovation by Craig D. Wegner, Bobbie Ann Mount, Christine M. Colvis

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Reconsideration of the current models of estimated kidney function‐based drug dose adjustment in older adults: The role of biological age by Radin Alikhani, Manjunath P. Pai

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Analysis of the Korean generic medicine market: Factors affecting the market share of generic medicines by Dong‐Sook Kim, Jihye Shin, Jusun Chung

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The Bioequivalence and Effect of Food on the Pharmacokinetics of a Fixed‐Dose Combination Tablet Containing Rosuvastatin and Ezetimibe in Healthy Japanese Subjects by Chisato Nishida, Yuki Matsumoto, Katsukuni Fujimoto, Masayoshi Shirakawa, Rebecca Ellen Wrishko, Martin Otto Behm, Kenichi Furihata

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Safety, tolerability, pharmacokinetics, and pharmacodynamics of a TLR7 agonist prodrug RO6870868 in healthy volunteers by Joseph F. Grippo, Ilia Folitar, Sharon Passe, Qiudi Jiang, Ignacio Rodriguez, Scott H. Fettner, Elizabeth Calleja

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