Search Results - "translational science"

A randomized, placebo‐controlled study to evaluate safety and pharmacokinetics of ART‐001 with a novel oral pediatric formulation in healthy subjects by Akira Tanaka, Naoto Uemura, Kanako Kuniyeda, Haruhi Ando, Toshinori Higashi, Hiroshi Nagabukuro

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Influence of novel CYP2C‐haplotype on proton pump inhibitor pharmacokinetics in children by Kathryn E. Kyler, Andrea Gaedigk, Susan Abdel‐Rahman, Vincent S. Staggs, Robin E. Pearce, Paul Toren, J. Steven Leeder, Valentina Shakhnovich

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Predicting lung exposure of intramuscular niclosamide as an antiviral agent: Power‐law based pharmacokinetic modeling by Taeheon Kim, Woojin Jung, Sangeun Cho, Gwanyoung Kim, Hwi‐yeol Yun, Jung‐woo Chae

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An Innovative Disease‐Drug‐Trial Framework to Guide Binge Eating Disorder Drug Development: A Case Study for Topiramate by Shamir N. Kalaria, Susan L. McElroy, Jogarao Gobburu, Mathangi Gopalakrishnan

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In vitro PK/PD modeling of tyrosine kinase inhibitors in non‐small cell lung cancer cell lines by Linda Wanika, Neil D. Evans, Martin Johnson, Helen Tomkinson, Michael J. Chappell

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A Strategy to Treat COVID‐19 Disease With Targeted Delivery of Inhalable Liposomal Hydroxychloroquine: A Preclinical Pharmacokinetic Study by Tien‐Tzu Tai, Tzung‐Ju Wu, Huey‐Dong Wu, Yi‐Chen Tsai, Hui‐Ting Wang, An‐Min Wang, Sheue‐Fang Shih, Yee‐Chun Chen

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Clinical Utility of Pharmacogene Panel‐Based Testing in Patients Undergoing Percutaneous Coronary Intervention by Nihal El Rouby, Adel Alrwisan, Taimour Langaee, Gloria Lipori, Dominick J Angiolillo, Francesco Franchi, Alberto Riva, Amanda Elsey, Julie A. Johnson, Larisa H. Cavallari, Almut G. Winterstein

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An exploratory machine learning approach to identify placebo responders in pharmacological binge eating disorder trials by Rahul K. Goyal, Shamir N. Kalaria, Susan L. McElroy, Mathangi Gopalakrishnan

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Hydrazinocurcumin Induces Apoptosis of Hepatocellular Carcinoma Cells Through the p38 MAPK Pathway by Hongtao He, Kuangyuan Qiao, Chao Wang, Wuhan Yang, Zhuo Xu, Zhilei Zhang, Yuming Jia, Chong Zhang, Li Peng

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Retrospective Analysis Using Pharmacokinetic/Pharmacodynamic Modeling and Simulation Offers Improvements in Efficiency of the Design of Volunteer Infection Studies for Antimalarial... by Kayla Ann Andrews, Joel S. Owen, James McCarthy, David Wesche, Nathalie Gobeau, Thaddeus H. Grasela, Jörg J. Möhrle

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Evolving drug regulatory landscape in China: A clinical pharmacology perspective by Weifeng Tang, Ying Huang, Diansong Zhou, Yao Huang, Yingxue Chen, Song Ren, Yan Li, Shengqian Wu, Xiaoying Zhao, Xuyang Song, Haidong Wang, Yuwen Jin, Hongtao Yu, Li Zhang, Yunfei Li, David Boulton, Kevin Shen

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Impact of SLCO1B1 Genetic Variation on Rosuvastatin Systemic Exposure in Pediatric Hypercholesterolemia by Jonathan B. Wagner, Susan Abdel‐Rahman, Andrea Gaedigk, Roger Gaedigk, Geetha Raghuveer, Vincent S. Staggs, Leon Van Haandel, J. Steven Leeder

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Genetics of drug‐induced liver injury: Current knowledge and future prospects by Ann K. Daly

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Investor initiatives program: Public‐private partnerships to expedite commercialization for NCI‐funded small business entrepreneurs by Brittany Connors, Xing‐Jian Lou, Ashim Subedee, Kehui Zhang, Michael Weingarten, Deepa Narayanan

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A RATional choice for translational research? by Tim Aitman, Paraminder Dhillon, Aron M. Geurts

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How resilient were we in 2021? Results of a LinkedIn Survey including biomedical and pharmaceutical professionals using the Benatti Resiliency Model by Songmao Zheng, Karthik Venkatakrishnan, Beth Benatti Kennedy

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Postmarket safety communications on drugs approved in Japan: A 25‐year analysis by Yusuke Tanaka, Mototsugu Tanaka, Haruna Miyazawa, Ryohei Terashima, Makoto Miyazawa, Mutsuhiro Ikuma, Yoshihiko Tomita

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Genetic predisposition and high exposure to colistin in the early treatment period as independent risk factors for colistin‐induced nephrotoxicity by Sumith K. Mathew, Aaron Chapla, Padmanaban Venkatesan, Vishnu Eriyat, Blessed Winston Aruldhas, Ratna Prabha, Michael N. Neely, Shoma V. Rao, Subramani Kandasamy, Binu Susan Mathew

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Translatability of in vitro potency to clinical efficacious exposure: A retrospective analysis of FDA‐approved targeted small molecule oncology drugs by Naoki Kotani, Kiyomi Ito

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Emergency department admissions induced by drug-drug interactions in the elderly: A cross‐sectional study by Louis Letinier, Iris Pujade, Perrine Duthoit, Grégoire Evrard, Francesco Salvo, Cédric Gil‐Jardine, Antoine Pariente

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