Search Results - "translational science"

Optimizing the Therapeutic Window of Targeted Drugs in Oncology: Potency‐Guided First‐in‐Human Studies by Matthew J. Goldstein, Malte Peters, Barbara L. Weber, Charles B. Davis

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Risk factors for the development of sepsis in patients with cirrhosis in intensive care units by Yan‐qi Kou, Yu‐ping Yang, Shen‐shen Du, Xiongxiu Liu, Kun He, Wei‐nan Yuan, Biao Nie

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Feasibility study for a fully decentralized clinical trial in participants with functional constipation symptoms by Ki Young Huh, Woo Kyung Chung, Jiyeon Park, SeungHwan Lee, Min‐Gul Kim, Jaeseong Oh, Kyung‐Sang Yu

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Evidence‐based rationale for low dose nivolumab in critically ill patients with sepsis‐induced immunosuppression by Demy A. C. van denHaak, Leila‐Sophie Otten, Hans J. P. M. Koenen, Ruben L. Smeets, Berber Piet, Peter Pickkers, Matthijs Kox, Rob ter Heine

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Assessment of drug-drug interaction potential with EDP‐305, a farnesoid X receptor agonist, in healthy subjects by Alaa Ahmad, Nathalie Adda

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FlyBase portals to human disease research using Drosophila models by Gillian H. Millburn, Madeline A. Crosby, L. Sian Gramates, Susan Tweedie, the FlyBase Consortium

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Using an animal model to predict the effective human dose for oral multiple sclerosis drugs by Wei Liu, Zhiheng Yu, Ziyu Wang, Emmanuelle L. Waubant, Suodi Zhai, Leslie Z. Benet

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Predictors of potential clinically harmful drug-drug interactions at the medical wards in the University of Benin Teaching Hospital, Benin City by Oseremen Godstime Oriaifo, Abimbola Olubukunola Opadeyi, Tracy Oseremen Oriaifo, Ambrose Ohumagho Isah

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Estimation of the benefit from pre‐emptive genotyping based on the nationwide cohort data in South Korea by Ki Young Huh, Sejung Hwang, Joo Young Na, Kyung‐Sang Yu, In‐Jin Jang, Jae‐Yong Chung, Seonghae Yoon

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Paired comparisons of venetoclax concentration in cerebrospinal fluid, bone marrow, and plasma in acute leukemia patients by Yuan Jian, Feifei Han, Ying Zhu, Chuanying Geng, Yanru Zhang, Yin Wu, Yun Leng, Wenming Chen, Zhuoling An, Hong‐Hu Zhu

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Evolving Role for Pharmacotherapy in NAFLD/NASH by Suzanna L. Attia, Samir Softic, Marialena Mouzaki

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Clinical pharmacology information in regulatory submissions and labeling: A comparative analysis of orphan and non‐orphan drugs approved by the FDA by Julie Hsieh, Martina Sahre, Xinning Yang, Rajanikanth Madabushi, Anuradha Ramamoorthy

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Population pharmacokinetic/pharmacodynamic modeling of the psychedelic experience induced by N,N‐dimethyltryptamine - Implications for dose considerations by Emma Eckernäs, Christopher Timmermann, Robin Carhart‐Harris, Daniel Röshammar, Michael Ashton

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The use of microtracers in food‐effect trials: An alternative study design for toxic drugs with long half‐lives exemplified by the case for alectinib by L. T. van derHeijden, N. Steeghs, J. H. Beijnen, A. D. R. Huitema, T. P. C. Dorlo

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Clinical pharmacokinetics and pharmacodynamics of venetoclax, a selective B‐cell lymphoma‐2 inhibitor by Ahmed Hamed Salem, Rajeev M. Menon

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Variability in In Vitro OATP1B1/1B3 Inhibition Data: Impact of Incubation Conditions on Variability and Subsequent Drug Interaction Predictions by Savannah J. McFeely, Tasha K. Ritchie, Isabelle Ragueneau‐Majlessi

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Engaging African American Faith Leaders as Partners in Ethical Research by Deborah J. Moon, Carol Bailey Nichols, John M. Wallace, Aliya Durham

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Dose‐dependent induction of CYP3A activity by St. John's wort alone and in combination with rifampin by Nicolas Hohmann, Anna S. Friedrichs, Jürgen Burhenne, Antje Blank, Gerd Mikus, Walter E. Haefeli

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Correlation Analysis Among the Level of IL‐35, Microvessel Density, Lymphatic Vessel Density, and Prognosis in Non‐Small Cell Lung Cancer by Tenglong Zhang, Jing Nie, Xiaojiang Liu, Zenglei Han, Ning Ding, Kai Gai, Yang Liu, Ling Chen, Chengye Guo

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Exposure-Response Relationship of Certolizumab Pegol and Achievement of Low Disease Activity and Remission in Patients With Rheumatoid Arthritis by Stéphane Paul, Hubert Marotte, Arthur Kavanaugh, Philippe Goupille, Tore K. Kvien, Marc deLongueville, Denis Mulleman, William J. Sandborn, Niels Vande Casteele

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