Search Results - "translational science"

Development of a Modified Score System as Prediction Model for Successful Vaginal Birth After Cesarean Delivery by Yan‐Ping Xing, Xin‐Ying Qi, Xue‐Zhen Wang, Feng‐Zhen Yang

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Examining the effects of the HIV‐1 protein Tat and morphine on antiretroviral accumulation and distribution within the brain by Austin M. Jones, Kara M. Rademeyer, Elias P. Rosen, Silas Contaifer, Dayanjan Wijesinghe, Kurt F. Hauser, MaryPeace McRae

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Effects of elagolix on the pharmacokinetics of omeprazole and its metabolites in healthy premenopausal women by Ahmed Nader, Nael M. Mostafa, Elaine Kim, Mohamad Shebley

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Evaluation of Drug-Drug Interactions of Rucaparib and CYP1A2, CYP2C9, CYP2C19, CYP3A, and P‐gp Substrates in Patients With an Advanced Solid Tumor by Jim J. Xiao, Dorota Nowak, Rodryg Ramlau, Monika Tomaszewska‐Kiecana, Piotr J. Wysocki, Jeff Isaacson, Jeri Beltman, Eileen Nash, Robert Kaczanowski, Gerhard Arold, Simon Watkins

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Savor the flavor: A randomized double‐blind study assessing taste‐enhanced placebo analgesia in healthy volunteers by Matthias Zunhammer, Gerrit Goltz, Maximilian Schweifel, Boris A. Stuck, Ulrike Bingel

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A disease model predicting placebo response and remission status of patients with ulcerative colitis using modified Mayo score by Anita Moein, Jurgen Langenhorst, Elodie L. Plan, Jin Y. Jin, Matts Kågedal, Nastya Kassir

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Drug-drug interactions between pemafibrate and statins on pharmacokinetics in healthy male volunteers: Open‐label, randomized, 6‐sequence, 3‐period crossover studies by Tomohiro Kamimura, Neil Hounslow, Hideki Suganami, Ryohei Tanigawa

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Gene polymorphism and prediction of toxicity to platinum‐based chemotherapy in patients with gynecologic cancer by Xuan Huang, Junmin Li, Xiaoying Pang, Jialei Zhu, Jiaqian Pan, Yueyan Li, Jing Tang

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Phase I study in healthy participants to evaluate safety, tolerability, and pharmacokinetics of inhaled nezulcitinib, a potential treatment for COVID‐19 by Nathan D. Pfeifer, Arthur Lo, David L. Bourdet, Kenneth Colley, Dave Singh

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Bioequivalence of two oral formulations of tebipenem pivoxil hydrobromide in healthy subjects by Vipul K. Gupta, Gina Patel, Leanne Gasink, Floni Bajraktari, Yang Lei, Akash Jain, Praveen Srivastava, Angela K. Talley

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Analysis of a large cohort of pancreatic cancer transcriptomic profiles to reveal the strongest prognostic factors by Máté Posta, Balázs Győrffy

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High‐dose intranasal insulin in an adaptive dose‐escalation study in healthy human participants by Florian Schmitzberger, Jennifer Fowler, Cindy H. Hsu, Manjunath P. Pai, Robert W. Neumar, William J. Meurer, Robert Silbergleit

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A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age‐dependent differences in absorption by Eva J. Streekstra, Márton Kiss, Jeroen van denHeuvel, Johan Nicolaï, Petra van denBroek, Sanne M. B. I. Botden, Martijn W. J. Stommel, Lara vanRijssel, Anna‐Lena Ungell, Evita van deSteeg, Frans G. M. Russel, Saskia N. deWildt

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Virtual screening FDA approved drugs against multiple targets of SARS‐CoV‐2 by Hualou Liang, Liang Zhao, Xiajing Gong, Meng Hu, Hongbin Wang

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Immune‐viral dynamics modeling for SARS‐CoV‐2 drug development by Youfang Cao, Wei Gao, Luzelena Caro, Julie A. Stone

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MicroRNA‐100 Enhances Autophagy and Suppresses Migration and Invasion of Renal Cell Carcinoma Cells via Disruption of NOX4‐Dependent mTOR Pathway by Xiumin Liu, Lili Zhong, Ping Li, Peng Zhao

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New score models for assessing disease activity in Crohn's disease based on bowel ultrasound and biomarkers: Ideal surrogates for endoscopy or imaging by Qingyang Zhou, Qingli Zhu, Wei Liu, Wenbo Li, Li Ma, Mengsu Xiao, Jingjuan Liu, Hong Yang, Jiaming Qian

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A microdosing framework for absolute bioavailability assessment of poorly soluble drugs: A case study on cold‐labeled venetoclax, from chemistry to the clinic by Amr Alaarg, Rajeev Menon, David Rizzo, Yemin Liu, Jeffrey Bien, Tricia Elkinton, Timothy Grieme, Lutz R. Asmus, Ahmed Hamed Salem

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Identification of Susceptibility Genes to Allergic Rhinitis by Gene Expression Data Sets by Kai Xue, Jingpu Yang, Yin Zhao, Jinzhang Cheng, Zonggui Wang

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Dosage Regimens for Meropenem in Children with Pseudomonas Infections Do Not Meet Serum Concentration Targets by Hazem E. Hassan, Vijay Ivaturi, Jogarao Gobburu, Thomas P. Green

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