Search Results - "translational science"

First‐in‐human study with SAR445088: A novel selective classical complement pathway inhibitor by Timothy Chow, Pirouz Shamszad, Christopher Vinnard, Esther Yoon, Julia Belinski, Irene Karpenko, Laurent Perrin, Kristen Auwarter, Michael Storek, Howard Surks, Nancy Wong, Yehuda Z. Cohen

Connect to this object online.

A phase I, first‐in‐human, randomized dose‐escalation study of anti‐activated factor XII monoclonal antibody garadacimab by Andrew McKenzie, Anthony Roberts, Sourabh Malandkar, Henrike Feuersenger, Con Panousis, Dipti Pawaskar

Connect to this object online.

Cardiovascular risk of urate‐lowering drugs: A study using the National Database of Health Insurance Claims and Specific Health Checkups of Japan by Sono Sawada, Kazuhiro Kajiyama, Haruka Shida, Ryota Kimura, Yuki Nakazato, Toyotaka Iguchi, Yukio Oniyama, Chieko Ishiguro, Yoshiaki Uyama

Connect to this object online.

Comparison of the effects of perineural or intravenous dexamethasone on thoracic paravertebral block in Ivor‐Lewis esophagectomy: A double‐blind randomized trial by Yan Zhang, Lu Qiao, Wenping Ding, Kai Wang, Yuqiong Chen, Liwei Wang

Connect to this object online.

Association between statin use and dry eye disease in patients with hyperlipidemia: A population‐based retrospective cohort study by Yong‐Wei Wang, Sian‐De Liu, Guan‐Ling Lin, Evelyn‐Jou‐Chen Huang, Joseph Jordan Keller, Li‐Hsuan Wang

Connect to this object online.

Comparing machine learning and deep learning models to predict cognition progression in Parkinson's disease by Edgar A. Bernal, Shu Yang, Konnor Herbst, Charles S. Venuto

Connect to this object online.

Clinical versus fixed warfarin dosing and the impact on quality of anticoagulation (The ClinFix trial) by Amr M. Fahmi, Ahmed El Bardissy, Mohamed Omar Saad, Mohamed Nabil Elshafei, Loulia Bader, Ahmed Mahfouz, Mohamed Kasem, Osama Abdelsamad, Abdelnasser Elzouki, Christina L. Aquilante, Fatima Mraiche, Ezeldin Soaly, Ihab El Madhoun, Nidal Asaad, Abdulrahman Arabi, Eman Alhmoud, Hazem Elewa

Connect to this object online.

Kinetics of myelin breakdown products: A labeling study in patients with progressive multiple sclerosis by Kawita M. S. Kanhai, Sebastiaan C. Goulooze, Jeroen van derGrond, Amy C. Harms, Thomas Hankemeier, Ajay Verma, Gersham Dent, Juan Chavez, Henri Meijering, Geert Jan Groeneveld

Connect to this object online.

Continuous versus intermittent infusion of human antithrombin III concentrate in the immediate postoperative period after liver transplantation by Bo Rim Kim, Leerang Lim, YoungRok Choi, Nam‐Joon Yi, Kwang‐Woong Lee, Kyung‐Suk Suh, Kyung‐Sang Yu, Jin Young Sohn, Raewon Jeong, Jaeseong Oh, Ho Geol Ryu

Connect to this object online.

Molecular identification of HLA‐B75 serotype markers by qPCR: A more inclusive pharmacogenetic approach before carbamazepine prescription by Kanoot Jaruthamsophon, Pornsiri Sangmanee, Oradawan Plong‐on, Chariyawan Charalsawadi, Chonlaphat Sukasem, Areerat Hnoonual

Connect to this object online.

Using exploratory pharmacokinetic and pharmacodynamic analyses to predict the probability of flu‐like symptoms in healthy volunteers and patients with chronic hepatitis B treated w... by Qiudi Jiang, Yuchen Zhang, Dan Duan, Sylvie Retout, Ruchi Upmanyu, Katerina Glavini, Miriam Triyatni, Yonghong Zhu, Joseph F. Grippo, Yuyan Jin

Connect to this object online.

Utilizing venous occlusion plethysmography to assess vascular effects: A study with buloxibutid, an angiotensin II type 2 receptor agonist by Erik Rein‐Hedin, Folke Sjöberg, Cecilia Ganslandt, Johan Skoog, Helene Zachrisson, Thomas Bengtsson, Carl‐Johan Dalsgaard

Connect to this object online.

The interactive walkway provides fit‐for‐purpose fall‐risk biomarkers in the elderly: Comparison of zolpidem and suvorexant by Ingrid Koopmans, Daphne Geerse, Lara deRidder, Melvyn Roerdink, Maria Joanna Juachon, Clemens Muehlan, Jasper Dingemanse, Joop vanGerven, Geert Jan Groeneveld, Rob Zuiker

Connect to this object online.

Pharmacokinetics and pharmacodynamics of itepekimab in adults with moderate‐to‐severe atopic dermatitis: Results from two terminated phase II trials by Matthew P. Kosloski, Emma Guttman‐Yassky, Michael J. Cork, Margitta Worm, Dong‐Ho Nahm, Xiaoping Zhu, Marcella K. Ruddy, Sivan Harel, Mohamed A. Kamal, Hélène Goulaouic, Christine R. Xu, Elena Avetisova, John D. Davis, Michael C. Nivens, Arsalan Shabbir, Allen Radin

Connect to this object online.

Ubrogepant Is Not Associated With Clinically Meaningful Elevations of Alanine Aminotransferase in Healthy Adult Males by Wendy Ankrom, Phung Bondiskey, Chi‐Chung Li, John Palcza, Wen Liu, Marissa F. Dockendorf, Catherine Matthews, Deborah Panebianco, Tom Reynders, John A. Wagner, Abhijeet Jakate, Sofie Mesens, Walter K. Kraft, Eugene E. Marcantonio

Connect to this object online.

MB09, a denosumab biosimilar candidate: Biosimilarity demonstration in a phase I study in healthy subjects by Monika Tomaszewska‐Kiecana, Elisabete Carapuça, Amalia Florez‐Igual, Javier Queiruga‐Parada

Connect to this object online.

In vivo human keyhole limpet hemocyanin challenge in early phase drug development: A systematic review by Philip G. Drennan, Dimitrios Karponis, Duncan Richards, Mark Coles, James N. Fullerton

Connect to this object online.

Genomewide association study identifies a novel variant associated with tacrolimus trough concentration in Chinese renal transplant recipients by Siyao Yang, Haixia Jiang, Chengcheng Li, Huijie Lu, Chuanjiang Li, Demei Ye, Huana Qi, Wenbin Xu, Xiaojie Bao, Nicola Maseko, Siqi Zhang, Ruifan Shao, Liang Li

Connect to this object online.

Integrated metabolomics analysis reveals mechanistic insights into variability in blood pressure response to thiazide diuretics and beta blockers by Mai Mehanna, Caitrin W. McDonough, Steven M. Smith, Yan Gong, John G. Gums, Arlene B. Chapman, Julie A. Johnson, Rhonda M. Cooper‐DeHoff

Connect to this object online.

Albumin to globulin ratio was associated with in‐stent restenosis and revascularization events after percutaneous coronary intervention by Rui Zhang, Zaixiao Tao, Jing Gong, Zhenjun Ji, Mingming Yang, Genshan Ma, Yongjun Li

Connect to this object online.