Search Results - "translational science"

Effect of vitamin D supplementation on circulating level of autophagosome protein LC3A, inflammation, and physical performance in knee osteoarthritis by Wacharapol Saengsiwaritt, Jiraphun Jittikoon, Usa Chaikledkaew, Tulyapruek Tawonsawatruk, Sittisak Honsawek, Wanvisa Udomsinprasert

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A mechanistic PK/PD model to enable dose selection of the potent anti‐tryptase antibody (MTPS9579A) in patients with moderate‐to‐severe asthma by Sharon M. Rymut, Lindsay M. Henderson, Victor Poon, Tracy L. Staton, Fang Cai, Siddharth Sukumaran, Horace Rhee, Ryan Owen, Saroja Ramanujan, Kenta Yoshida

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Real‐world evidence to support regulatory submissions: A landscape review and assessment of use cases by Golnoosh Alipour‐Haris, Xinyue Liu, Virginia Acha, Almut G. Winterstein, Mehmet Burcu

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Safety and tolerability of a 90‐minute rapid infusion of Sandoz biosimilar rituximab in B‐cell lymphoproliferative disorders in a real‐world setting by Ana Muntañola, José María Arguiñano‐Pérez, Julio Dávila, Sonia González deVillambrosia, Cecilia Carpio, Ana Jiménez‐Ubieto, Antonio Salar, the GELTAMO (Grupo español de linfomas y trasplante de médula ósea)

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Noninvasive assessment of carotid plaque with subharmonic aided pressure estimation from a US contrast agent: A preliminary study by Rui Li, Yukang Zhang, Shuai Zheng, Linggang Cheng, Yanfen Zhang, Zhiguang Chen, Wen He, Wei Zhang

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Learning health system benefits: Development and initial validation of a framework by Lisa C. Welch, Sarah K. Brewer, Titus Schleyer, Denise Daudelin, Rechelle Paranal, Joe D. Hunt, Ann M. Dozier, Anna Perry, Alyssa B. Cabrera, Cheryl L. Gatto

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Pharmacokinetics of Sugammadex Dosed by Actual and Ideal Body Weight in Patients With Morbid Obesity Undergoing Surgery by Kate Mostoller, Rebecca Wrishko, Lata Maganti, W. Joseph Herring, Mariëlle vanZutphen‐van Geffen

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Ribavirin aerosol in hospitalized adults with respiratory distress and COVID‐19: An open‐label trial by Garyfallia Poulakou, Maxime Barakat, Robert J. Israel, Marcelo R. Bacci, Virazole Collaborator Group for COVID‐19 Respiratory Distress

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Comparison of the influence of light between circularly polarized and linearly polarized smartphones on dry eye symptoms and asthenopia by Yujie Mou, Xiao Shen, Kelan Yuan, Xin Wang, Fangli Fan, Yaying Wu, Chunyang Wang, Xiuming Jin

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An implementation science focused practice‐based research network for rural community pharmacies: RURAL‐CP by Delesha M. Carpenter, Stephanie Kiser, Megan Smith, Patricia Mashburn, Salisa C. Westrick, Tessa J. Hastings, Ashley Hannings, Meagen Rosenthal, Jure Baloh, Abigail Gamble, Tyler C. Melton, Geoffrey M. Curran

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Application of a patient‐centered reverse translational systems‐based approach to understand mechanisms of an adverse drug reaction of immune checkpoint inhibitors by Sarah Kim, Gezim Lahu, Majid Vakilynejad, Theodoros G. Soldatos, David B. Jackson, Lawrence J. Lesko, Mirjam N. Trame

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Feasibility of preemptive pharmacogenetic testing and improvement of medication treatment satisfaction among medically underserved patients by Christelle Lteif, Elizabeth Eddy, Joshua Terrell, Larisa H. Cavallari, John Malaty, Julio D. Duarte

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Quantification of Adverse Drug Reactions Related to Drug Switches in The Netherlands by Pieter J. Glerum, Marc Maliepaard, Vincent deValk, Joep H.G. Scholl, Florence P.A.M. vanHunsel, Eugène P. vanPuijenbroek, David M. Burger, Kees Neef

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Longitudinal evaluation of azithromycin and cytokine concentrations in amniotic fluid following one‐time oral dosing in pregnancy by Rupsa C. Boelig, Edwin Lam, Ankit Rochani, Gagan Kaushal, Amanda Roman, Walter K. Kraft

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Effect of selenium on thyroid autoimmunity and regulatory T cells in patients with Hashimoto's thyroiditis: A prospective randomized‐controlled trial by Yifang Hu, Wenwen Feng, Huanhuan Chen, He Shi, Lin Jiang, Xuqin Zheng, Xiaoyun Liu, Wensong Zhang, Yaoqi Ge, Yun Liu, Dai Cui

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Predictors of Adverse Events and Determinants of the Voriconazole Trough Concentration in Kidney Transplantation Recipients by Yi‐Chang Zhao, Xiao‐Bin Lin, Bi‐Kui Zhang, Yi‐wen Xiao, Ping Xu, Feng Wang, Da‐Xiong Xiang, Xu‐Biao Xie, Feng‐Hua Peng, Miao Yan

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Absolute oral bioavailability of milvexian spray‐dried dispersion formulation under fasted and fed conditions in healthy adult participants: An intravenous microtracer approach by Praneeth Jarugula, Sharif Soleman, Hyunmoon Back, Lisa J. Christopher, Dara Hawthorne, Ronald Aronson, Anh Bui, Angela Mirzac, Antoinette Ajavon‐Hartmann, Vidya Perera, Bindu Murthy, Samira Merali

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Implementing sensor‐based digital health technologies in clinical trials: Key considerations from the eCOA Consortium by Elena S. Izmailova, Danielle Middleton, Reem Yunis, Julia Lakeland, Kristen Sowalsky, Julia Kling, Alison Ritchie, Christine C. Guo, Bill Byrom, Scottie Kern

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A phase I thorough QT/QTc study evaluating therapeutic and supratherapeutic doses of avacopan in healthy participants by Shichang Miao, Peter Staehr, Ezra Tai, Borje Darpo, Hongqi Xue, Danielle Armas, Kenneth Webster, Rajneet K. Oberoi

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Allelic variation in HLA‐DRB1 is associated with development of antidrug antibodies in cancer patients treated with atezolizumab that are neutralizing in vitro by Christian Hammer, Jane Ruppel, Lynn Kamen, Julie Hunkapiller, Ira Mellman, Valerie Quarmby

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