Search Results - "translational science"

Hydroxychloroquine for treatment of non‐hospitalized adults with COVID‐19: A meta‐analysis of individual participant data of randomized trials by Oriol Mitjà, Gilmar Reis, David R. Boulware, Adam M. Spivak, Ammar Sarwar, Christine Johnston, Brandon Webb, Michael D. Hill, Davey Smith, Peter Kremsner, Marla Curran, David Carter, Jim Alexander, Marc Corbacho, Todd C. Lee, Katherine Huppler Hullsiek, Emily G. McDonald, Rachel Hess, Michael Hughes, Jared M. Baeten, Ilan Schwartz, Luanne Metz, Lawrence Richer, Kara W. Chew, Eric Daar, David Wohl, Michael Dunne

Connect to this object online.

Pharmacogenetics of taxane‐induced neurotoxicity in breast cancer: Systematic review and meta‐analysis by Alberto Guijosa, Ana Freyria, Jose Rodrigo Espinosa‐Fernandez, Francisco J. Estrada‐Mena, Ana Sofía Armenta‐Quiroga, Maria Fernanda Ortega‐Treviño, Rodrigo Catalán, Bani Antonio‐Aguirre, Cynthia Villarreal‐Garza, Andric C. Perez‐Ortiz

Connect to this object online.

Age associations with tacrolimus and mycophenolic acid pharmacokinetics in stable Black and White kidney transplant recipients: Implications for health inequities by Kathleen M. Tornatore, Kristopher Attwood, Rocco C. Venuto, Brian Murray

Connect to this object online.

Associations of HLA genetic variants with carbamazepine‐induced cutaneous adverse drug reactions: An updated meta‐analysis by Mohitosh Biswas, Maliheh Ershadian, John Shobana, Ai‐Hoc Nguyen, Chonlaphat Sukasem

Connect to this object online.

Associations of striatal dopamine transporter binding with motor and non‐motor symptoms in early Parkinson's disease by Zhengjie Yang, Yijie Xie, Kaixin Dou, Liying Yang, Anmu Xie

Connect to this object online.

Design and utilization of the colorectal and pancreatic neoplasm virtual biorepository: An early detection research network initiative by Waqas Amin, Harpreet Singh, Lynda Ann Dzubinski, Robert E Schoen, Anil V Parwani

Connect to this object online.

Exploratory window‐of‐opportunity trial to investigate the tumor pharmacokinetics/pharmacodynamics of the IAP antagonist Debio 1143 in patients with head and neck cancer by Carlos Gomez‐Roca, Caroline Even, Christophe Le Tourneau, Neus Basté, Jean‐Pierre Delord, Jerome Sarini, Sebastien Vergez, Stephane Temam, Caroline Hoffmann, Philippe Rochaix, Edith Borcoman, Bruno Gavillet, Elisabeth Rouits, Annick Ménétrey, Franck Brichory, Daniela Purcea, Gregoire Vuagniaux, Claudio Zanna

Connect to this object online.

Prognostic value of severe acute respiratory syndrome coronavirus‐2 viral load and antibodies in patients hospitalized with COVID‐19 by Rebecca N. Bauer, Anastasia Teterina, Haridha Shivram, Jacqueline McBride, Carrie M. Rosenberger, Fang Cai, Min Bao, Larry Tsai, Oliver Gordon, Ivan T. Lee, Jeffrey J. Wallin, Danielle Porter, Kavita Juneja, Gregory Camus, Ivan O. Rosas, Steffen Wildum

Connect to this object online.

A randomized, cross‐over trial of metoprolol succinate formulations to evaluate PK and PD end points for therapeutic equivalence by Scott A. Mosley, Sarah Kim, Nihal El Rouby, Karthik Lingineni, Valvanera Vozmediano Esteban, Yan Gong, Yiqing Chen, David Estores, Kairui Feng, Hyewon Kim, Minori Kinjo, Taimour Langaee, Zhichuan Li, Siegfried O. F. Schmidt, Julie A. Johnson, Reginald F. Frye, Lanyan  (Lucy), Liang Zhao, Philip F. Binkley, Stephan Schmidt, Larisa H. Cavallari

Connect to this object online.

Rationale and design for a pragmatic randomized trial to assess gene‐based prescribing for SSRIs in the treatment of depression by Lindsay J. Hines, Russell A. Wilke, Rachel Myers, Carol A. Mathews, Michelle Liu, Jordan F. Baye, Natasha Petry, Emily J. Cicali, Benjamin Q. Duong, Erica Elwood, Leslie Hulvershorn, Khoa Nguyen, Michelle Ramos, Azita Sadeghpour, R. Ryanne Wu, Lloyda Williamson, Kristin Wiisanen, Deepak Voora, Rajbir Singh, Kathryn V. Blake, James W. Murrough, Simona Volpi, Geoffrey S. Ginsburg, Carol R. Horowitz, Lori Orlando, Hrishikesh Chakraborty, Paul Dexter, Julie A. Johnson, Todd C. Skaar, Larisa H. Cavallari, Sara L. Van Driest, Josh F. Peterson, the IGNITE Pragmatic Trials Network

Connect to this object online.

The relationship between Taekwondo training habits and injury: a survey of a collegiate Taekwondo population by Covarrubias N, Bhatia S, Campos LF, Nguyen DV, Chang EY

Connect to this object online.

Safety, pharmacokinetics and target engagement of novel RIPK1 inhibitor SAR443060 (DNL747) for neurodegenerative disorders: Randomized, placebo‐controlled, double‐blind phase I/Ib... by Maurits F. J. M. Vissers, Jules A. A. C. Heuberger, Geert Jan Groeneveld, Jerome Oude Nijhuis, Peter Paul De Deyn, Salah Hadi, Jeffrey Harris, Richard M. Tsai, Andres Cruz‐Herranz, Fen Huang, Vincent Tong, Rebecca Erickson, Yuda Zhu, Kimberly Scearce‐Levie, Jennifer Hsiao‐Nakamoto, Xinyan Tang, Megan Chang, Brian M. Fox, Anthony A. Estrada, Robert J. Pomponio, Miguel Alonso‐Alonso, Moshe Zilberstein, Nazem Atassi, Matthew D. Troyer, Carole Ho

Connect to this object online.

Association of UGT1A1*6, UGT1A1*28, or ABCC2 c.3972C>T genetic polymorphisms with irinotecan‐induced toxicity in Asian cancer patients: Meta‐analysis by Chalirmporn Atasilp, Mohitosh Biswas, Pimonpan Jinda, Nutthan Nuntharadthanaphong, Jiratha Rachanakul, Yaowaluck Hongkaew, Natchaya Vanwong, Surasak Saokaew, Chonlaphat Sukasem

Connect to this object online.

Applying the CiPA approach to evaluate cardiac proarrhythmia risk of some antimalarials used off‐label in the first wave of COVID‐19 by Annie Delaunois, Matthew Abernathy, Warren D. Anderson, Kylie A. Beattie, Khuram W. Chaudhary, Julie Coulot, Vitalina Gryshkova, Simon Hebeisen, Mark Holbrook, James Kramer, Yuri Kuryshev, Derek Leishman, Isabel Lushbough, Elisa Passini, Will S. Redfern, Blanca Rodriguez, Eric I. Rossman, Cristian Trovato, Caiyun Wu, Jean‐Pierre Valentin

Connect to this object online.

Pharmacokinetic/pharmacodynamic modeling of drug interactions at the P2Y12 receptor between selatogrel and oral P2Y12 antagonists by Andrea Henrich, Christian Hove Claussen, Jasper Dingemanse, Andreas Krause

Connect to this object online.

Safety, pharmacokinetics, pharmacodynamics, and antitumor activity of SAR439459, a TGFβ inhibitor, as monotherapy and in combination with cemiplimab in patients with advanced solid... by Joaquina C. Baranda, Debbie Robbrecht, Ryan Sullivan, Bernard Doger, Armando Santoro, Minal Barve, Jean‐Jacques Grob, Oliver Bechter, Maria Vieito, Maria Jose deMiguel, Dirk Schadendorf, Melissa Johnson, Clemence Pouzin, Cathy Cantalloube, Rui Wang, Jooyun Lee, Xiaofei Chen, Brigitte Demers, Amele Amrate, Giovanni Abbadessa, F. Stephen Hodi

Connect to this object online.

Implementing a pragmatic clinical trial to tailor opioids for acute pain on behalf of the IGNITE ADOPT PGx investigators by Larisa H. Cavallari, Emily Cicali, Kristin Wiisanen, Roger B. Fillingim, Hrishikesh Chakraborty, Rachel A. Myers, Kathryn V. Blake, Bolanle Asiyanbola, Jordan F. Baye, Wesley H. Bronson, Kelsey J. Cook, Erica N. Elwood, Chancellor F. Gray, Yan Gong, Lindsay Hines, Joseph Kannry, Natalie Kucher, Sheryl Lynch, Khoa A. Nguyen, Aniwaa Owusu Obeng, Victoria M. Pratt, Hernan A. Prieto, Michelle Ramos, Azita Sadeghpour, Rajbir Singh, Marc Rosenman, Petr Starostik, Cameron D. Thomas, Emma Tillman, Paul R. Dexter, Carol R. Horowitz, Lori A. Orlando, Josh F. Peterson, Todd C. Skaar, Sara L. Van Driest, Simona Volpi, Deepak Voora, Hari K. Parvataneni, Julie A. Johnson, for the IGNITE Pragmatic Trials Network

Connect to this object online.

A novel cross-institutional college internship program to train future diverse leaders in clinical research with data-driven approaches to assess impact by Julia Derk, Julia Derk, Julia Derk, Kafui Dzirasa, Kafui Dzirasa, Kafui Dzirasa, Kafui Dzirasa, Tracie Locklear, Tracie Locklear

Connect to this object online.

Economic evaluation of eribulin as second-line treatment for metastatic breast cancer in South Korea by Tremblay G, Majethia U, Breeze JL, Kontoudis I, Park J

Connect to this object online.

Combined use of right ventricular coupling and pulmonary arterial elastance as a comprehensive stratification approach for right ventricular function by Yihang Wu, Pengchao Tian, Lin Liang, Yuyi Chen, Jiayu Feng, Boping Huang, Liyan Huang, Xuemei Zhao, Jing Wang, Jingyuan Guan, Xinqing Li, Yuhui Zhang, Jian Zhang

Connect to this object online.