Search Results - "tyrosine kinase"

Cryptotanshinone enhances the efficacy of Bcr-Abl tyrosine kinase inhibitors via inhibiting STAT3 and eIF4E signalling pathways in chronic myeloid leukaemia by Rubin Cheng, Yilan Huang, Yun Fang, Qirui Wang, Meixiu Yan, Yuqing Ge

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Synthesis and In Vitro Cytotoxicity of the 4-(Halogenoanilino)-6-bromoquinazolines and Their 6-(4-Fluorophenyl) Substituted Derivatives as Potential Inhibitors of Epidermal Growth Factor Receptor Tyrosine Kinase by Malose Jack Mphahlele, Hugues K. Paumo, Yee Siew Choong

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miR-146b-5p Enhances the Sensitivity of NSCLC to EGFR Tyrosine Kinase Inhibitors by Regulating the IRAK1/NF-κB Pathway by Yi-Nan Liu, Meng-Feng Tsai, Shang-Gin Wu, Tzu-Hua Chang, Tzu-Hsiu Tsai, Chien-Hung Gow, Hsin-Yi Wang, Jin-Yuan Shih

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Saracatinib, a Src Tyrosine Kinase Inhibitor, as a Disease Modifier in the Rat DFP Model: Sex Differences, Neurobehavior, Gliosis, Neurodegeneration, and Nitro-Oxidative Stress by Meghan Gage, Marson Putra, Logan Wachter, Kylie Dishman, Megan Gard, Crystal Gomez-Estrada, Thimmasettappa Thippeswamy

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Receptor tyrosine kinase-like orphan receptor 1 inhibitor strictinin exhibits anti-cancer properties against highly aggressive androgen-independent prostate cancer by Vignesh Sivaganesh, Bela Peethambaran

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Design and green synthesis of novel quinolinone derivatives of potential anti-breast cancer activity against MCF-7 cell line targeting multi-receptor tyrosine kinases by Mohamed Mokhtar, Khadijah S. Alghamdi, Nesreen S. Ahmed, Dina Bakhotmah, Tamer S. Saleh

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Upregulation of ICAM-1 Expression on J774.2 Macrophages by Endotoxin Involves Activation of NF-κB but not Protein Tyrosine Kinase: Comparison to Induction of iNOS by Hartmut Ruetten, Christoph Thiemermann, Mauro Perretti

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Targeting <i>BRAF</i> Activation as Acquired Resistance Mechanism to EGFR Tyrosine Kinase Inhibitors in <i>EGFR</i>-Mutant Non-Small-Cell Lung Cancer by Frank Aboubakar Nana, Sebahat Ocak

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Development of a novel Bruton's tyrosine kinase inhibitor that exerts anti-cancer activities potentiates response of chemotherapeutic agents in multiple myeloma stem cell-like cells by Weam Othman Elbezanti, Weam Othman Elbezanti, Omar S. Al-Odat, Omar S. Al-Odat, Robert Chitren, Robert Chitren, Jaikee Kumar Singh, Sandeep Kumar Srivastava, Krishne Gowda, Shantu Amin, Gavin P. Robertson, Venkatesh V. Nemmara, Subash C. Jonnalagadda, Tulin Budak-Alpdogan, Manoj K. Pandey

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Meta-Analysis of Aidi Injection and First-Generation Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Therapy in Treating Advanced Non-Small Cell Lung Cancer by Na Xiao MD, Hailang He MD, Jing Wang MD, Li Zhang MD, Brandon Chow, Fanchao Feng MD, Yong Xu MD, Jingyi Huang MD, Xianmei Zhou MD, Rui Dong MD

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CD4 T cells from patients with chronic myeloid leukemia are resistant to HIV-1 proviral integration and transcription after prolonged withdrawal of treatment with tyrosine kinase inhibitors by Lorena Vigón, Sara Rodríguez-Mora, Elena Mateos, Valentín García, Juan Ambrosioni, Nuria Climent, Guiomar Bautista, José Alcamí, Juan Luis Steegmann, Montserrat Plana, José M. Miró, Vicente Planelles, María Rosa López Huertas, Mayte Coiras

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Repurposing Synthetic Congeners of a Natural Product Aurone Unveils a Lead Antitumor Agent Inhibiting Folded P-Loop Conformation of MET Receptor Tyrosine Kinase by Ahmed H. E. Hassan, Cai Yi Wang, Cheol Jung Lee, Hye Rim Jeon, Yeonwoo Choi, Suyeon Moon, Chae Hyeon Lee, Yeon Ju Kim, Soo Bin Cho, Kazem Mahmoud, Selwan M. El-Sayed, Sang Kook Lee, Yong Sup Lee

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Smoking in preeclamptic women is associated with higher birthweight for gestational age and lower soluble fms-like tyrosine kinase-1 levels: a nested case control study by Kahn Susan R, Almeida Nisha D, McNamara Helen, Koren Gideon, Genest Jacques, Dahhou Mourad, Platt Robert W, Kramer Michael S

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A short in-frame deletion in NTRK1 tyrosine kinase domain caused by a novel splice site mutation in a patient with congenital insensitivity to pain with anhidrosis by Arístegui Javier, Garrote Elisa, Rodríguez Jose A, Sarasola Esther, García-Barcina Maria J

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Nuclear Pore Glycoprotein 62 Genetic Variant rs9523 is Associated with Clinical Outcomes of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Lung Adenocarcinoma Patients by Park JE, Hong MJ, Lee SY, Lee JH, Choi JE, Kang HG, Do SK, Jeong JY, Shin KM, Lee WK, Choi SH, Lee YH, Seo HW, Yoo SS, Lee J, Cha SI, Kim CH, Park JY

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EGFR T790M detection and osimertinib treatment response evaluation by liquid biopsy in lung adenocarcinoma patients with acquired resistance to first generation EGFR tyrosine kinase inhibitors by Chenguang Li, Rui Jia, Hailin Liu, Bin Zhang, Changli Wang

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A preliminary study on drug switching strategy for second-line therapy after combination treatment of tyrosine kinase inhibitors and immune checkpoint inhibitors for unresectable hepatocellular carcinoma by Renguo Guan, Renguo Guan, Renguo Guan, Chengyou Yu, Chengyou Yu, Chengyou Yu, Shaohua Li, Shaohua Li, Shaohua Li, Jie Mei, Jie Mei, Jie Mei, Wei Wei, Wei Wei, Wei Wei, Rongping Guo, Rongping Guo, Rongping Guo

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Diosgenin and Monohydroxy Spirostanol from <i>Prunus amygdalus var amara</i> Seeds as Potential Suppressors of EGFR and HER2 Tyrosine Kinases: A Computational Approach by Mohammed Helmy Faris Shalayel, Ghassab M. Al-Mazaideh, Abdulkareem A. Alanezi, Afaf F. Almuqati, Meshal Alotaibi

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Meta-Analysis of Aidi Injection and First-Generation Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Therapy in Treating Advanced Non-Small Cell Lung Cancer by Na Xiao MD, Hailang He MD, Jing Wang MD, Li Zhang MD, Brandon Chow, Fanchao Feng MD, Yong Xu MD, Jingyi Huang MD, Xianmei Zhou MD, Rui Dong MD

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COST-EFFECTIVENESS ANALYSIS OVER USE OF TYROSINE KINASE INHIBITORS (TASIGNA AND GLEEVEC) FOR TREATMENT OF CHRONIC MYELOID LEUKEMIA IN THE CHRONIC PHASE AS FIRST-LINE THERAPY FOR DE NOVO PATIENTS by R. I. Yagudina, A. Yu. Kulikov, I. A. Komarov

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