Search Results - "tyrosine kinase"

Lung cancer - the role of immuno-oncology and the importance of pembrolizumab in its therapy by Jakub Jarosz, Anna Wesołowska, Paweł Różanowski

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Sustained antiviral response against in vitro HIV-1 infection in peripheral blood mononuclear cells from people with chronic myeloid leukemia treated with ponatinib by Mario Manzanares, Mario Manzanares, Fernando Ramos-Martín, Sara Rodríguez-Mora, Sara Rodríguez-Mora, Guiomar Casado-Fernández, Guiomar Casado-Fernández, Clara Sánchez-Menéndez, Clara Sánchez-Menéndez, Clara Sánchez-Menéndez, Alicia Simón-Rueda, Alicia Simón-Rueda, Elena Mateos, Elena Mateos, Miguel Cervero, Miguel Cervero, Adam M. Spivak, Vicente Planelles, Montserrat Torres, Montserrat Torres, Valentín García-Gutiérrez, Mayte Coiras, Mayte Coiras

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A pan-cancer analysis of FAT atypical cadherin 4 (FAT4) in human tumors by Weili Mao, Jiajing Zhou, Jie Hu, Kui Zhao, Zhenling Fu, Jun Wang, Kaili Mao

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Sitravatinib as a potent FLT3 inhibitor can overcome gilteritinib resistance in acute myeloid leukemia by Yvyin Zhang, Peihong Wang, Yang Wang, Yang Shen

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Genetic profiling of primary and secondary tumors from patients with lung adenocarcinoma and bone metastases reveals targeted therapy options by Long Huang, Xiao-Liu Jiang, Hong-Bin Liang, Jian-Cheng Li, Li-Han Chin, Jian-Ping Wei, Rui-Ru Wang, Jing Cai, Qiang Xiong, Lien-Tu Wang, David S. Cram, An-Wen Liu

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Role of gonadotropin-releasing hormone (GnRH) in ovarian cancer by Emons Günter, Gründker Carsten

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The Development of a Web-Based, Patient-Centered Intervention for Patients With Chronic Myeloid Leukemia (CMyLife): Design Thinking Development Approach by Ector, Geneviève ICG, Westerweel, Peter E, Hermens, Rosella PMG, Braspenning, Karin AE, Heeren, Barend CM, Vinck, Oscar MF, de Jong, Jan JM, Janssen, Jeroen JWM, Blijlevens, Nicole MA

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Membranous Insulin-like Growth Factor-1 Receptor (IGF1R) Expression Is Predictive of Poor Prognosis in Patients with Epidermal Growth Factor Receptor ()-Mutant Lung Adenocarcinoma by Eunhyang Park, Soo Young Park, Hyojin Kim, Ping-Li Sun, Yan Jin, Suk Ki Cho, Kwhanmien Kim, Choon-Taek Lee, Jin-Haeng Chung

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Identification of afatinib-associated ADH1B and potential small-molecule drugs targeting ADH1B for hepatocellular carcinoma by Yongxu Zhou, Yongxu Zhou, Liang Yu, Liang Yu, Peng Huang, Peng Huang, Xudong Zhao, Risheng He, Yunfu Cui, Bo Pan, Chang Liu

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Impact of the Gastric Acid Suppressant Use on the Safety and Effectiveness of EGFR-TKIs: A Systematic Review and Meta-Analysis by Xin Du, Wei Liu, Ken Chen, Ziyu Wang, Xinyi Li, Li Yang, Xiaohui Xie

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MicroRNA 138 Upregulation is Associated with Decreasing Levels of CCND1 Gene Expression and Promoting Cell Death in Human Prostate Cancer Cell Lines by Nasrin Haghighi-Najafabadi, Shima Fayaz, Mahboubeh Berizi, Ghazal Haddad, Pezhman Fard-Esfahani

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Network pharmacology combined with metabolomics to explore the mechanism for Lonicerae Japonicae flos against respiratory syncytial virus by Jie Ding, Jing Li, Zhe Zhang, Yaxuan Du, Yuhong Liu, Ping Wang, Haitao Du

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Comparison of neurotoxic potency between a novel chinbotulinumtoxinA with onabotulinumtoxinA, incobotulinumtoxinA and lanbotulinumtoxinA in rats by Feng Y, Liu WC, Pan LZ, Jiang C, Zhang CX, Lu YX, Nie ZY, Jin LJ

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The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway by Zakia A. Abdelhamed, Subaashini Natarajan, Gabrielle Wheway, Christopher F. Inglehearn, Carmel Toomes, Colin A. Johnson, Daniel J. Jagger

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Interleukin-10 and soluble tumor necrosis factor receptor II are potential biomarkers of Plasmodium falciparum infections in pregnant women: a case-control study from Nanoro, Burki... by E. Ruizendaal, H. D. F. H. Schallig, J. Bradley, M. Traore-Coulibaly, P. Lompo, U. d'Alessandro, S. Scott, F. Njie, S. H. Zango, O. Sawadogo, M. D. de Jong, H. Tinto, P. F. Mens

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Safety, pharmacokinetics, and pharmacodynamics of sofnobrutinib, a novel non‐covalent BTK inhibitor, in healthy subjects: First‐in‐human phase I study by Kyoko Miyamoto, Robert M. Miller, Christine Voors‐Pette, Jart A. F. Oosterhaven, Marieke van denDobbelsteen, Katsuhiro Mihara, Marian Geldof, Yuji Sato, Naomi Matsuda, Shirou Kirita, Masaaki Sawa, Akinori Arimura

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Exploration of the key active ingredients and mechanisms of Sparganii Rhizoma-Curcumae Rhizoma compatible formulation against human colorectal cancer through network pharmacology a... by Hongyan Lin, Dongxuan Ai, Xinling Wang, Shuaijun Cui, Xinghong Li, Bangmei Ye, Lingyu Ruan, Jing Xu, Liqun Wang

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A novel drug-like water-soluble small molecule Focal Adhesion Kinase (FAK) activator promotes intestinal mucosal healing by Qinggang Wang, Ricardo Gallardo-Macias, Emilie E. Vomhof-DeKrey, Rashmi Gupta, Svetlana A. Golovko, Mikhail Y. Golovko, Sema Oncel, Vadim J. Gurvich, Marc D. Basson

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Safety, Tolerability, Pharmacokinetics, Target Occupancy, and Concentration‐QT Analysis of the Novel BTK Inhibitor Evobrutinib in Healthy Volunteers by Andreas Becker, Emily C. Martin, David Y. Mitchell, Roland Grenningloh, Andrew T. Bender, Julien Laurent, Harald Mackenzie, Andreas Johne

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Evaluation of chronic drug-induced electrophysiological and cytotoxic effects using human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) by C. Altrocchi, K. Van Ammel, M. Steemans, M. Kreir, F. Tekle, A. Teisman, D. J. Gallacher, H. R. Lu

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