Search Results - Francis Poulenc~

Discovery of indole-3-butyric acid derivatives as potent histone deacetylase inhibitors by Yiming Chen, Lihui Zhang, Lin Zhang, Qixiao Jiang, Lei Zhang

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Effect of freezing on recombinant hepatitis E vaccine by Kelei Li, Fangyu Dong, Fan Gao, Lianlian Bian, Shiyang Sun, Ruixiao Du, Yalin Hu, Qunying Mao, Haifa Zheng, Xing Wu, Zhenglun Liang

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Discovery and SAR analysis of 5-chloro-4-((substituted phenyl)amino)pyrimidine bearing histone deacetylase inhibitors by Lin Zhang, Yiming Chen, Fahui Li, Lihui Zhang, Jinhong Feng, Lei Zhang

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Inhibitors of histone deacetylase 6 based on a novel 3-hydroxy-isoxazole zinc binding group by Pasquale Linciano, Luca Pinzi, Silvia Belluti, Ugo Chianese, Rosaria Benedetti, Davide Moi, Lucia Altucci, Silvia Franchini, Carol Imbriano, Claudia Sorbi, Giulio Rastelli

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Regioselective approach to colchiceine tropolone ring functionalization at C(9) and C(10) yielding new anticancer hybrid derivatives containing heterocyclic structural motifs by Krystian Pyta, Natalia Skrzypczak, Piotr Ruszkowski, Franz Bartl, Piotr Przybylski

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2H-chromene and 7H-furo-chromene derivatives selectively inhibit tumour associated human carbonic anhydrase IX and XII isoforms by Lisa Sequeira, Simona Distinto, Rita Meleddu, Marco Gaspari, Andrea Angeli, Filippo Cottiglia, Daniela Secci, Alessia Onali, Erica Sanna, Fernanda Borges, Eugenio Uriarte, Stefano Alcaro, Claudiu T. Supuran, Elias Maccioni

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Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment of Neisseria gonorrhoeae by Nader S. Abutaleb, Ahmed E. M. Elhassanny, Alessio Nocentini, Chad S. Hewitt, Ahmed Elkashif, Bruce R. Cooper, Claudiu T. Supuran, Mohamed N. Seleem, Daniel P. Flaherty

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Design and synthesis of naphthalimide group-bearing thioglycosides as novel β-N-acetylhexosaminidases inhibitors by Shengqiang Shen, Wei Chen, Lili Dong, Qing Yang, Huizhe Lu, Jianjun Zhang

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Evaluation of N-alkyl isatins and indoles as acetylcholinesterase and butyrylcholinesterase inhibitors by Kaitlyn N. Alcorn, Isabelle A. Oberhauser, Matthew D. Politeski, Todd J. Eckroat

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Discovery of novel dual-active 3-(4-(dimethylamino)phenyl)-7-aminoalcoxy-coumarin as potent and selective acetylcholinesterase inhibitor and antioxidant by Gabriela Alves de Souza, Soraia John da Silva, Catarina de Nigris Del Cistia, Paulo Pitasse-Santos, Lucas de Oliveira Pires, Yulli Moraes Passos, Yraima Cordeiro, Cristiane Martins Cardoso, Rosane Nora Castro, Carlos Mauricio R. Sant'Anna, Arthur Eugen Kümmerle

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Discovery of cyanopyridine scaffold as novel indoleamine-2,3-dioxygenase 1 (IDO1) inhibitors through virtual screening and preliminary hit optimisation by Xi Xu, Jie Ren, Yinghe Ma, Hongting Liu, Quanjin Rong, Yifan Feng, Yameng Wang, Yu Cheng, Ruijia Ge, Zhiyu Li, Jinlei Bian

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Effects of NS2B-NS3 protease and furin inhibition on West Nile and Dengue virus replication by Jenny Kouretova, M. Zouhir Hammamy, Anton Epp, Kornelia Hardes, Stephanie Kallis, Linlin Zhang, Rolf Hilgenfeld, Ralf Bartenschlager, Torsten Steinmetzer

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Applications and challenges in designing VHH-based bispecific antibodies: leveraging machine learning solutions by Michael Mullin, James McClory, Winston Haynes, Justin Grace, Nathan Robertson, Gino van Heeke

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Synthesis and carbonic anhydrase activating properties of a series of 2-amino-imidazolines structurally related to clonidine1 by Niccolò Chiaramonte, Soumia Maach, Caterina Biliotti, Andrea Angeli, Gianluca Bartolucci, Laura Braconi, Silvia Dei, Elisabetta Teodori, Claudiu T. Supuran, Maria Novella Romanelli

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Watermelon: setup and validation of an in silico fragment-based approach by Miriana Di Stefano, Salvatore Galati, Lisa Piazza, Francesca Gado, Carlotta Granchi, Marco Macchia, Antonio Giordano, Tiziano Tuccinardi, Giulio Poli

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Discovery of potent histone deacetylase inhibitors with modified phenanthridine caps by Wenli Fan, Lin Zhang, Xuejiang Wang, Haiyong Jia, Lei Zhang

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Rational design of heat stable lyophilized rotavirus vaccine formulations by Madhu Madan, Deepa Sikriwal, Gaurav Sharma, Nidhi Shukla, Ashwani Kumar Mandyal, Sachin Kale, Davinder Gill

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New indolesulfonamide derivatives targeting the colchicine site of tubulin: synthesis, anti-tumour activity, structure-activity relationships, and molecular modelling by Alba Vicente-Blázquez, Myriam González, Manuel Medarde, Faustino Mollinedo, Rafael Peláez

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Design, synthesis, and biological evaluation of thiazole/thiadiazole carboxamide scaffold-based derivatives as potential c-Met kinase inhibitors for cancer treatment by Xiang Nan, Qiu-Xu Wang, Shao-Jun Xing, Zhi-Gang Liang

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HPLC-based activity profiling for pharmacologically and toxicologically relevant natural products - principles and recent examples by Matthias Hamburger

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