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Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension
Published 2020Table of Contents: “…PART I: Basic Science of Pulmonary Development and Pulmonary Arterial Disease -- 1 Perspective for Part I -- 2 The alveolar stem cell niche of the mammalian lung -- 3 Lung development and Notch signalling -- 4 Specialized smooth muscle cell progenitors in pulmonary hypertension -- 5 Diverse Pharmacology of Prostacyclin Mimetics: Implications for Pulmonary Hypertension -- 6 Endothelial-to-mesenchymal transition in pulmonary hypertension -- 7 Extracellular vesicles, MicroRNAs and Pulmonary Hypertension -- 8 Roles of Tbx4 in the lung mesenchyme for airway and vascular development -- 9 A lacZ reporter transgenic mouse line revealing the development of pulmonary artery -- 10 Roles of stem cell antigen-1 in the pulmonary endothelium -- 11 Morphological characterization of pulmonary microvascular disease in bronchopulmonary dysplasia caused by hyperoxia in newborn mice -- 12 Involvement of CXCR4 and stem cells in a rat model of pulmonary arterial hypertension -- 13 Ca2+ signal through inositol trisphosphate receptors for cardiovascular development and pathophysiology of pulmonary arterial hypertension -- PART II: Abnormal pulmonary circulation in the developing lung and heart -- 14 Perspective for Part II -- 15 Pathophysiology of Pulmonary Circulation in Congenital Heart Disease -- 16 Development of Novel Therapies for Pulmonary Hypertension by Clinical Application of Basic Research -- 17 Using Patient-Specific Induced Pluripotent Stem Cells to Understand and Treat Pulmonary Arterial Hypertension -- 18 Modeling pulmonary arterial hypertension using induced pluripotent stem cells -- 19 Dysfunction and restoration of endothelial cell communications in Pulmonary Arterial Hypertension: Therapeutic implications -- 20 Inflammatory Cytokines in the Pathogenesis of Pulmonary Arterial Hypertension -- 21 Genotypes and Phenotypes of Chinese Pediatric Patients with Idiopathic and Heritable Pulmonary Arterial Hypertension- Experiences from A Single Center -- 22 Fundamental Insight into Pulmonary Vascular Disease : Perspectives from Pediatric PAH in Japan -- 23 Risk stratification in paediatric pulmonary arterial hypertension -- 24 The Adaptive Right Ventricle in Eisenmenger Syndrome: Potential Therapeutic Targets for Pulmonary Hypertension -- 25 Impaired right coronary vasodilator function in pulmonary hypertensive rat assessed by in vivo synchrotron microangiography -- 26 Relationship between mutations in ENG and ALK1 gene and the affected organs in hereditary hemorrhagic telangiectasia -- 27 A genetic analysis for patients with pulmonary arterial hypertension -- 28 Evaluation and visualization of right ventricle using three dimensional echocardiography -- 29 Pulmonary hypertension associated with post-operative Tetralogy of Fallot -- 30 Microscopic Lung Airway Abnormality and Pulmonary Vascular Disease Associated with Congenital Systemic to Pulmonary Shunt -- 31 Respiratory syncytial virus infection in infants with heart and lung diseases -- PART III: Ductus arteriosus: bridge over troubled vessels -- 32 Perspective for Part III -- 33 The ductus arteriosus, a vascular outsider, in relation to the pulmonary circulation -- 34 Molecular, genetic, and pharmacological modulation of the ductus arteriosus: KATP channels as novel drug targets -- 35 New mediators in the biology of the ductus arteriosus: Lessons from the chicken embryo -- 36 Constriction of the Ductus Arteriosus with KATP Channel Inhibitors -- 37 New insights on how to treat patent ductus arteriosus -- 38 Antenatal Administration of Betamethasone Contributes to Intimal thickening of the Ductus Arteriosus -- 39 Prostaglandin E-EP4-mediated fibulin-1 up-regulation plays a role in intimal thickening of the ductus arteriosus -- 40 Transcriptional profiles in the chicken ductus arteriosus during hatching -- 41 Inhibition of Cyclooxygenase Contracts Chicken Ductus Arteriosus -- 42 Prostaglandin E2 receptor EP4 inhibition constricts the rat ductus arteriosus -- 43 Dilatation of the Ductus Arteriosus by Diazoxide in Fetal and Neonatal Rats -- 44 The Effect of Long-term Administration of Plostaglandin E1 on Morphological Changes in Ductus Arteriosus -- 45 Significance of SGK1 as a protein kinase transcriptionally regulated by ALK1 signaling in vascular endothelial cells -- 46 Fabrication of Implantable Human Arterial Graft by Periodic Hydrostatic Pressure -- 47 Optimum preparation of Candida albicans cell wall extra (CAWE) for the mouse model of Kawasaki disease -- PART IV: Development and Regeneration of the Cardiovascular System -- 48 Perspective for Part IV -- 49 Advances in the second heart field -- 50 Novel cardiac progenitors for all components of the heart except for the right ventricle -- 51 Regional and TBX5-dependent gene expression in the atria: Implications for pulmonary vein development and atrial fibrillation -- 52 The Endocardium as a Master Regulator of Ventricular Trabeculation -- 53 The Role of Alternative mRNA Splicing in Heart Development -- 54 Progress in the Generation of Multiple Lineage Human-iPSC-derived 3D Engineered Cardiac Tissues for Cardiac Repair -- 55 Quantification of contractility in stem cell derived cardiomyocytes -- 56 A neurotrophic factor receptor GFRA2, a specific surface antigen for cardiac progenitor cells, regulates the process of myocardial compaction -- 57 Cardiac cell specification and differentiation by the defined factors -- 58 A Temporo-Spatial Regulation of Sema3c is Essential for Interaction of Progenitor Cells during Cardiac Outflow Tract Development -- 59 Spatiotemporally restricted developmental alterations in the anterior and secondary heart fields cause distinct conotruncal heart defects -- 60 Significance of transcription factors in the mechanisms of great artery malformations -- 61 The different c-kit expression in human induced pluripotent stem (iPS) cells between with feeder cells and without feeder cells -- 62 Establishment of induced pluripotent stem cells from immortalized B cell lines and their differentiation into cardiomyocytes -- 63 Establishment of an in vitro LQT3 model, using induced pluripotent stem cells from LQT3 patient-derived cardiomyocytes -- 64 Genetic Assessments for clinical courses of Left ventricle noncompaction -- 65 Elucidating the pathogenesis of congenital heart disease in the era of next-generation sequencing.…”
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L'Internet des objets : Quels enjeux pour l'Europe
Published 2009DOAB: download the publication
DOAB: description of the publication
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Preparation of Space Experiments
Published 2020DOAB: download the publication
DOAB: description of the publication
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How Megaprojects Are Damaging Nigeria and How to Fix It A Practical Guide to Mastering Very Large Government Projects /
Published 2022Table of Contents: “…-- References -- 3 Structure of the Investigation -- 3.1 Overview of the Approach Taken in This Study -- 3.2 Construction and Execution of the Survey -- 3.3 Construction of the Sample of Projects -- 3.4 Construction of the Case Studies -- Appendix: Full Questionnaire as It Was Administered -- Our Request -- Project Variables -- References -- 4 A Description of the 38 Matched Projects -- 4.1 Lagos-Ibadan Express Road -- 4.2 Lagos-Badagry Express Road -- 4.3 Third Mainland Bridge -- 4.4 Second Niger Bridge -- 4.5 Egbin Power Station -- 4.6 Calabar Power Station -- 4.7 Zungeru Hydropower Plant -- 4.8 Delta State (Oghareki) Power Plant -- 4.9 Shiroro Hydroelectric Power Station -- 4.10 Omoku Power Plant Station -- 4.11 Mambilla Hydroelectric Power -- 4.12 Ajaokuta Steel Project -- 4.13 Kanji Dam -- 4.14 Otukpo Dam -- 4.15 Nigeria Satellite 2 -- 4.16 Nigeria Satellite 1 -- 4.17 Airtel Nigeria -- 4.18 Nigerian Telecommunications Limited (NITEL) -- 4.19 Godswill Akpabio International Stadium -- 4.20 (Samuel) Ogbemudia Stadium -- 4.21 Abuja International Airport -- 4.22 Lagos MMA2 Airport -- 4.23 Yenagoa International Cargo Airport -- 4.24 Jigawa Airport Project -- 4.25 Tin Can Island Port -- 4.26 Calabar Seaport -- 4.27 Victoria Garden City (VGC) Housing Estate -- 4.28 Festac Town Federal Housing Estate -- 4.29 1004 Housing Estate -- 4.30 Abuja Mass Federal Housing Project -- 4.31 Olusegun Obasanjo Presidential Library -- 4.32 Abuja National Library -- 4.33 Nigerian Youth Empowerment Scheme (N-Power) -- 4.34 Nigeria Subsidy Reinvestment and Empowerment Programme (SURE-P) -- 4.35 Lagos State Waste Management Authority (LAWMA) -- 4.36 Cleaner Lagos Initiative (Visionscape) -- 4.37 University College Teaching Hospital (UCH) Ibadan -- 4.38 University of Abuja Teaching Hospital (UATH) -- References -- 5 Insights from the Analysis of the Questionnaires -- 5.1 Variable Distributions and Variable Capability to Detect Differences Across Projects -- 5.1.1 Each Respondent Type Adds Unique Perspectives and Information -- 5.1.2 The Variables Capture Robust Differences Between Abandoned and Completed Projects -- 5.2 Condensing Variables into Aggregated Success Factors -- 5.2.1 Approach -- 5.2.2 Identifying the Factors -- 5.3 Econometric Prediction of Project Completion -- 5.4 Econometric Prediction of Cost and Schedule Overruns for Completed Projects -- 5.4.1 Effect of Variables on Budget Overruns -- 5.4.2 Effect of Variables on Schedule Overruns -- 5.5 The Corrosive Effect of Corruption -- Appendix 1 Correlations Among Independent Variables Across All 114 Responses -- Appendix 2 Factor Analysis -- Appendix 3 Specification of the Logistical Regression -- Appendix 4 The Logistical Completion Probability Regression by Respondent Group -- Appendix 5 Robustness Analysis: Cost Overrun Regressions by Respondent Group -- Appendix 6 Robustness Analysis: Schedule Overrun Regressions by Respondent Group -- 6 Two Library Projects -- 6.1 The National Library of Nigeria in Abuja: An Abandoned Project -- 6.1.1 Project Initiation -- 6.1.2 Contract Signature and Execution -- 6.1.3 Conclusion -- 6.2 Olusegun Obasanjo Presidential Library: A Completed Project -- 6.2.1 Project Initiation -- 6.2.2 Project Execution and Outcome -- 6.2.3 The Difference Between the Two Projects: In the Words of Former President Obasanjo -- References -- 7 Two Bridge Projects -- 7.1 The Second Niger Bridge: A Stalled Project -- 7.1.1 Project Initiation -- 7.1.2 Contract Disputes and Recontracting -- 7.1.3 Continued Stalling -- 7.1.4 Diagnosis of the Reasons for Failure, in the Words of (Former) President Jonathan -- 7.1.5 Conclusion -- 7.2 The Third Mainland Bridge: A Completed Project -- 7.2.1 Introduction -- 7.2.2 Starting and Stalling -- 7.2.3 Restarting the Project Under President Babangida -- 7.2.4 Project Execution and Outcome -- 7.2.5 Conclusion -- References -- 8 Two Power Plants -- 8.1 Egbin Power Station, Ikorodu Lagos State: A Completed Project -- 8.1.1 Initiation and Completion -- 8.1.2 Success Conditions and Challenges -- 8.1.3 Privatization and Trouble -- 8.2 The Calabar Odukpani Power Station: Completed but with Little Delivery -- 8.2.1 Project Initiation -- 8.2.2 Project Complications and Delays -- 8.2.3 Delivery of the Calabar Power Station in 2015 -- 8.2.4 What Has Been Delivered? …”
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Politics as a Science A Prolegomenon
Published 2020DOAB: download the publication
DOAB: description of the publication
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