Isoniazid

|MedlinePlus = a682401 |DailyMedID = Isoniazid |pregnancy_AU = A |pregnancy_AU_comment = |routes_of_administration = By mouth, intramuscular, intravenous |ATC_prefix = J04 |ATC_suffix = AC01 |ATC_supplemental = |legal_AU = |legal_BR = |legal_CA = Rx-only |legal_CA_comment = |legal_DE = |legal_NZ = |legal_UK = |legal_US = Rx-only |legal_UN = |legal_status = |protein_bound = Very low (0–10%) |metabolism = liver; CYP450: 2C19, 3A4 inhibitor |elimination_half-life = 0.5–1.6h (fast acetylators), 2-5h (slow acetylators) |excretion = urine (primarily), feces |synonyms = isonicotinic acid hydrazide, isonicotinyl hydrazine, INH, INAH, INHA |CAS_number_Ref = |CAS_number = 54-85-3 |PubChem = 3767 |DrugBank_Ref = |DrugBank = DB00951 |ChemSpiderID_Ref = |ChemSpiderID = 3635 |UNII_Ref = |UNII = V83O1VOZ8L |KEGG_Ref = |KEGG = D00346 |KEGG2_Ref = |KEGG2 = C07054 |ChEBI_Ref = |ChEBI = 6030 |ChEMBL_Ref = |ChEMBL = 64 |NIAID_ChemDB = 007657 |IUPAC_name = Pyridine-4-carbohydrazide |C=6 | H=7 | N=3 | O=1 |SMILES = C1=CN=CC=C1C(=O)NN |StdInChI_Ref = |StdInChI = 1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10) |StdInChIKey_Ref = |StdInChIKey = QRXWMOHMRWLFEY-UHFFFAOYSA-N }}

Isoniazid, also known as isonicotinic acid hydrazide (INH), is an antibiotic used for the treatment of tuberculosis. For active tuberculosis, it is often used together with rifampicin, pyrazinamide, and either streptomycin or ethambutol. For latent tuberculosis, it is often used alone. It may also be used for atypical types of mycobacteria, such as ''M. avium'', ''M. kansasii'', and ''M. xenopi''. It is usually taken by mouth, but may be used by injection into muscle. Provided by Wikipedia