Genetic and Epigenetic Regulations of Tumor Progression and Metastasis

• その他の著者: Smolkova, Bozena (編集者), Earl, Julie (編集者), Kataki, Agapi (編集者)
• フォーマット: 電子媒体 図書の章
• 言語: 英語
• 出版事項: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• 主題: Medicine; Oncology; prostate cancer; metastasis; epithelial-to-mesenchymal transition (EMT); partial-EMT (p-EMT); Zeb1; DNA methylation; 5-azacytidine; lung adenocarcinoma; brain metastasis; omics data analysis; CDKN2A; p16; invasive ductal breast cancer; CDH1 gene; EMT genes; miRNA and mRNA expression; E-cadherin; HTR2B; STAT proteins; uveal melanoma; promoter; gene transcription; PDAC; inflammation; hypoxia; epithelial-to-mesenchymal transition; cancer proliferation; hepatocellular carcinoma; engineered exosomes; diagnostic biomarker; cancer therapy; angiogenesis; pericytes; adipose tissue; cell adhesion; endothelial cells; breast cancer; metastatic cascade; intra-tumor heterogeneity; mutational profile; adaptive responses; autophagy; tumor mutational burden; tumor microenvironment; waterpipe smoke; lung cancer; n/a; CYSLTR1; CYSLTR2; methylation; prognosis; colorectal cancer; EMT
• オンライン･アクセス: DOAB: download the publication; DOAB: description of the publication

Genetic aberrations and epigenetic modifications are critical drivers of cancer progression and metastasis. Although recurrent mutations in primary and metastatic cancers have been shown to be concordant, there are several metastasis-associated mutations responsible for resistance to specific therap...