Toxins Mr Hyde or Dr Jekyll?

• Other Authors: Ladant, Daniel (Editor), Prévost, Gilles (Editor), Popoff, Michel R. (Editor), Benoit, Evelyne (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Medicine; Medical toxicology; toxins; peptide chemistry; native chemical ligation; α-bungarotoxin; click chemistry; automated patch-clamp; fluorescent peptide; TE671 cells; nicotinic acetylcholine receptor; animal toxin; bacterial toxin; marine toxin; medical application; plant toxin; toxin function/activity; toxin receptor/target; toxin structure; Debaryomyces hansenii; Wickerhamomyces anomalus; Saccharomyces cerevisiae; PDR transporters; killer toxin; fetal adrenomedullary chromaffin cell; gambierol; potassium currents; calcium-activated K+ channels; ATP-sensitive K+ channels; catecholamine release; Clostridium tetani; Clostridium botulinum; botulinum neurotoxin; tetanus neurotoxin; toxin gene regulation; two-component system; small RNA; adenylate cyclase toxin; Bordetella pertussis; cyclic nucleotide; cAMP; spectrophotometric enzymatic assay; ASIC; sodium channels; peptide; PcTx1; APETx2; MitTx; mambalgin; pain; nociception; clostridial C3 toxin; C3bot; C3botE174Q; dendritic cells; macrophages; monocytes; stimulated emission depletion (STED); super-resolution microscopy; trained immunity; effector-triggered immunity; effector-triggered trained immunity; staphylococcal superantigen; enterotoxin; toxin pathogenicity; immunomodulation; molecular and cellular targets; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Toxins are biologically active substances produced by most kinds of living organisms, bacteria, fungi, plants, and animals. They present a vast diversity of molecular structures and target a wide variety of receptors involved in a range of physiological processes. As toxins are selected during evolu...