Immunotherapy in Hepatocellular Carcinoma

• Other Authors: Nishida, Naoshi (Editor), Kudo, Masatoshi (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Medicine; Oncology; cancer immunotherapy; TCGA; mutations; copy number variations; microRNAs; PD-1; PD-L1; hepatocellular carcinoma; predictive factors; immunotherapy; immune checkpoint inhibition; check-point inhibitors; liver disease; outcome; biomarkers; combination immunotherapy; immune-related adverse events (irAEs); hepatocellular carcinoma (HCC); alpha fetoprotein response; immune checkpoint inhibitor; unresectable hepatocellular carcinoma; a disintegrin and metalloprotease 9; nivolumab; natural killer; CTLA-4; combination therapy; PD-1 antibody; PD-L1 antibody; anti-VEGF inhibitor; molecular classification; immune phenotype; stem cell marker; oncogenic signal; β-catenin; genetic alteration; liver cancer; effectiveness; safety; HCC; molecular-targeted agent; TACE; tyrosine kinase inhibitor; CD14+ cells; programmed death 1 ligands; translational approaches; combination therapies; therapy resistance; predictive markers; tissue-resident memory CD8 T cells; immune checkpoint blockade
• Online Access: DOAB: download the publication; DOAB: description of the publication

Based on this evidence, a deep understanding of the immunological status and biological targets modulating immunological microenvironments should be quite informative for the development of future immunotherapy in HCC. From this point of view, this Special Issue will highlight the current state of t...