Precision Nutrition

• Other Authors: Palou, Andreu (Editor), Reynés, Barbara (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Research & information: general; Biology, life sciences; Food & society; dietary parameters; carbohydrate intake; obesity; single nucleotide polymorphism; CLOCK gene; rs3749474; sodium intake; hypertension; single-nucleotide polymorphism; personalized nutrition; dietary vitamin A; body fat; UCP; retinoic acid; PBMC; genetic variant; weight loss; nutrigenomics; dietary intervention; FTO gene; dietary protein; dietary carbohydrates; dietary fat; macronutrients; gene-diet interaction; glucose homeostasis; glaucoma; polygenetic-risk scores; gene-gene interaction; gene-nutrient interaction; precision medicine; childhood; insulin resistance; adipokine; metabolomics; biomarkers; ELOVL; metabolic alterations; Mexican population; Single Nucleotide Polymorphisms; pediatrics; cardiometabolic risk factors; precision nutrition; eating behavior; nutrigenetics; microbiota; metabolic syndrome; Mediterranean diet; genetic risk score; HELENA; adolescents; sex
• Online Access: DOAB: download the publication; DOAB: description of the publication

New scientific advances in different areas have allowed the design of more precise strategies for the prevention and treatment of metabolic disorders through nutrition. In this context emerges the term Precision Nutrition, a new approach that takes advantage of scientific knowledge about the interaction of internal and external environmental factors to develop dynamic and precise nutritional recommendations. Therefore, Precision Nutrition includes personalized advice based on genetics and well-documented gene-nutrient-phenotype interactions, as well as other factors such as individual metabolome, transcriptome, and microbiota profile; food behavior; and dietary, physical activity, and life-style habits; and the resulting interactomes. Precision Nutrition should be based at least on three sequential steps: conventional nutritional approaches (considering age, gender, and physiological states); the incorporation of nutritional and health status information (e.g., metabolites, physical and nutritional behavior); and the genetic baggage including multiomics functional integration.