Design, Production and Characterization of Peptide Antibodies

• Other Authors: Trier, Nicole Hartwig (Editor), Houen, Gunnar (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Research & information: general; Biology, life sciences; Biochemistry; 2xVH; IgG-like bispecifics; bivalent bispecific molecule; symmetrical bispecific; concomittant binding; soluble VH; antibody; heavy-chain dimer; heavy-chain antibody; crystal structure; single-domain antibody; Lassa virus; Arenaviridae family; MagPlex; protein; self-association; self-interaction; developability; in silico prediction; computational modeling; viscosity; dynamic light scattering; monoclonal antibodies; promoters; bidirectional; antibody production; upstream processing; anti-citrullinated protein antibodies; citrullinated peptides; epitopes; rheumatoid arthritis; calreticulin; epitope; enzyme-linked immunosorbent assay; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Antibodies are key reagents in diagnostics and experimental biology, capable of detecting numerous antigenic targets. Proteins are often in focus and are usually effective targets for antibody production. Occasionally, however, the native protein is known but not available, or a very specific target...