Risk Assessment of Nanomaterials Toxicity

• Other Authors: Hartwig, Andrea (Editor), van Thriel, Christoph (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Technology: general issues; nanotoxicology; titanium dioxide; synthetic amorphous silica; agglomerates and aggregates; realistic exposure in vitro; nanomaterials; agglomerates; air-liquid interface; pulmonary toxicity; metal-based nanoparticles and nanowires; solubility; intracellular bioavailability; oxidative reactivity; comet assay; FADU assay; engineered nanomaterials; DNA strand breaks; genotoxicity; ENM interference; hazard assessment; database; lung toxicity; study quality; nanoparticles; gene regulation; endocytosis; inflammation; NR4A1; interlaboratory comparison; minimal information; quality criteria; description standards; graphene; 2D; nanoplates; lung; inhalation; toxicity; in vitro; Cr2O3 particles; Cr(VI) release; cytotoxicity; gene expression profiles; DNA damage signaling; DNA repair proteins; oxidative stress; cell death pathways; NAMs-new approach methodologies; ALI-air-liquid interface; BEAS-2B; A549; NM-300K; DNA damage; chromosomal damage; cytokines; TiO2 NPs; titanium dental implants; 3D spheroids; osteoblasts; safe-by-design; hazard testing; in vitro methods; SAbyNA; advanced materials; carbon nanotubes; in vitro models; respiratory tract; bronchial epithelium; alveolar epithelium; ciliary beating frequency; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Regarding the increasing use of nanomaterials in almost every area of our daily life, toxicological risk assessment is one of the major requirements for their safe handling. Especially at workplaces, inhalation is the major route of exposure and potential toxicity, and effects on the lung need to be...