Fate of Antioxidants in Gut and Interaction of Gut Metabolites and Gut Microbiota

• Other Authors: Xu, Baojun (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Research & information: general; Biology, life sciences; Food & society; anthocyanins; berries; polyphenols; bioaccesibility; differential pulse voltammetry; first-pass metabolism; HPLC-ESI-QTOF-MS; apparent permeability; oxidative stress; inflammation; antioxidant; anthocyanin; phenolic acid; antioxidant capacity; medium chain fatty acids; short chain fatty acids; gut microbiome; Ougan (Citrus reticulata cv. Suavissima); polymethoxyflavones; gut microbiota; metabolism in vivo; metabolite identification; beneficial regulatory effect; Dendropanax morbifera; hepatoprotective; leaf extract; liver damage; alcoholism; oxidative damage; dietary polyphenols; metabolites; epigenetics; microflora; cardiometabolic complications; selenium; zinc; bioaccumulation; antioxidant capacities; intestinal microbiota; inhibition; metabolism; catabolism; biotransformation; bioactive compounds; health; diversity; dysbiosis; leaky gut; endotoxemia; fatty liver disease; ethanol; phytochemicals; quercetin; high-fat diet; insulin resistance; Bacillus amyloliquefaciens SC06; IPEC-J2; autophagy; apoptosis; AKT-FOXO
• Online Access: DOAB: download the publication; DOAB: description of the publication

It is widely accepted that antioxidants can help in disease prevention by effectively quenching free radicals or inhibiting damage caused by oxidative stress. However, the final fate of antioxidants in the gut, how antioxidant metabolites affect gut microbiota, and how gut microbiota affect the metabolism of antioxidants are not fully understood. This Special Issue collected the latest research findings and review articles, bringing together current research and critical thinking on the fate of phytochemical antioxidants in the gut and the role antioxidant gut metabolites play in reducing oxidative stress in various gut and metabolic diseases. Both in vitro and in vivo studies relating to any of the following topics will be considered: fate of antioxidants in the gut; antioxidative activities of phytochemicals in the digestive system; molecular mechanisms of phytochemical antioxidants in maintaining gut health; and interactions of antioxidant metabolites and gut microbiota.