Glutathione: Chemistry and Biochemistry

• Other Authors: Perjési, Pál (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Research & information: general; Biology, life sciences; cyclophosphamide; autoimmune diseases; glutathione; glutathione-S-transferase; polymorphism; glutaredoxin; iron-sulfur cluster; iron; S-glutathionylation; S-nitrosylation; GSH; nitrosoglutathione; redox-regulation; polymerized whey protein; physicochemical properties; pharmacokinetics; toxicity; chalcone; cysteine; thiols; Michael addition; diastereoselective addition; reactive oxygen species; oxidative stress; nanotoxicity; cell injury; fluorescence probes; brain; liquid chromatography; diode array detector; anticancer drugs; mechanisms of glutathione conjugation reaction; detoxification; bioactivation; sulodexide; endothelial cells; ischemia; apoptosis; GSSG; GCLc; GSS; redox potential; supramolecular arrangement; M06-2X/6-311++G(d,p); DFT; molecular docking; angiotensin-converting enzyme; cell; redox homeostasis; glutathionylation; glutathione system; glutathione enzyme; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

It has been known that cellular glutathione content and its speciation play a role, among others, in redox homeostasis, cell cycle control, immunological defense, and pathological abnormalities. Furthermore, it plays a significant role in the biotransformation of drugs and other endogenous or exogen...