Molecular Mechanisms of Synaptic Plasticity: Dynamic Changes in Neurons Functions

• Other Authors: Martella, Giuseppina (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Research & information: general; Biology, life sciences; autophagy; proteasome; immunoproteasome; mTOR; T-cells; glia; dopamine; glutamate; neuro-inflammation; glucocorticoids; noradrenaline; tyrosine hydroxylase; reticular formation; dopamine transporter; Parkinson's disease; PINK1; caspase-3; striatum; synaptic plasticity; long-term depression; brain networks; connectivity; Alzheimer's disease (AD); schizophrenia; long-term potentiation (LTP); synaptic scaling; resting state functional MRI (rs-fMRI); inflammation; multiple sclerosis; neuregulins; ErbB receptors; LTP; LTD; hippocampus; midbrain dopamine neurons; brain connectivity; brain development; gut-brain axis; neurodevelopmental diseases; neuronal cytoarchitecture; neuroplasticity; regulatory T cells; serotonin (5-HT); endocannabinoid system; spatial learning; dorsal striatum; amygdala; Circular Hole Board; AM251; mice; dystonia; D2 receptors; synapses; dopamine volume transmission; SNARE proteins; long-term potentiation; learning and memory; cognition; Schaffer collateral-CA1 synapses; tripartite synapse; neurovascular unit; systems biology; Glutamate; NMDA receptors; dendritic spines; brain disorders; transmission electron microscopy; human neurons; induced neural stem cells; synapse; synaptic vesicles; high contrast; inhibition; computational neuroscience; GABA; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

The human brain has hundreds of billions of neurons, and at least 7 million dendrites have been hypothesized to exist for each neuron, with over 100 trillion neuron-neuron, neuron-muscle, and neuron-endocrine cell synapses [1,2]. Our body continually receives stimuli from the outer environment, and...