Iron Metabolism, Redox Balance and Neurological Diseases

• Andere auteurs: Chang, Yan-Zhong (Redacteur)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Onderwerpen: Medicine; Pharmaceutical industries; glioma; ferroptosis; lipid peroxidation; molecular mechanisms; treatment; CHIR99021; glycogen synthesis kinase 3; classical Wnt signaling pathway; ferritin; Neuro-2a; cell stemness; MitoQ; PMMP; autophagy; radioprotection; energy phenotype; coenzyme Q10; tissue concentrations; therapeutics; Alzheimer's disease; dementia; vascular dementia; Lewy body dementia; IRP2; Hif2 inhibition; Fe-S clusters; ferritinophagy; microcytic anemia; iron homeostasis; iron dysregulation; inflammation; infection; cancer; iron chelation; glucose metabolism; NLRP3 inflammasome; insulin resistance; oxidative stress; CY-09; OTUD3; ER stress; IRE1α; XBP1s; Fortilin; intracellular iron homeostasis; neuroinflammation; neurodegenerative diseases; Nrf2; NF-κB; 4-HNE; Parkinson's disease; stroke; neurodevelopment; iron chelator; n/a
• Online toegang: DOAB: download the publication; DOAB: description of the publication

With the aging of the population, the incidence rate and number of elderly nervous system diseases have increased sharply. This event has brought huge problems to society. Despite significant efforts being made to explore new treatment options and drugs, the results have been limited. The reason may...