New Developments in the Pathogenesis of Rheumatoid Arthritis

• その他の著者: Sakkas, Lazaros I. (編集者)
• フォーマット: 電子媒体 図書の章
• 言語: 英語
• 出版事項: IntechOpen 2017
• 主題: Immunology; cytokines, microrna, biomarkers, epigenetics, microbiota, mirna
• オンライン･アクセス: DOAB: download the publication; DOAB: description of the publication

The pathogenesis of rheumatoid arthritis (RA) is incompletely understood. HLA class II alleles and T cells have been implicated for many years. The discovery of anticitrullinated peptide antibodies (ACPAs), along with the effectiveness of biological treatments targeting cytokines, such as TNF-?, IL-...