New Developments in the Pathogenesis of Rheumatoid Arthritis

• Autres auteurs: Sakkas, Lazaros I. (Éditeur intellectuel)
• Format: Électronique Chapitre de livre
• Langue: anglais
• Publié: IntechOpen 2017
• Sujets: Immunology; cytokines, microrna, biomarkers, epigenetics, microbiota, mirna
• Accès en ligne: DOAB: download the publication; DOAB: description of the publication

The pathogenesis of rheumatoid arthritis (RA) is incompletely understood. HLA class II alleles and T cells have been implicated for many years. The discovery of anticitrullinated peptide antibodies (ACPAs), along with the effectiveness of biological treatments targeting cytokines, such as TNF-?, IL-...