New Developments in the Pathogenesis of Rheumatoid Arthritis

• अन्य लेखक: Sakkas, Lazaros I. (संपादक)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: IntechOpen 2017
• विषय: Immunology; cytokines, microrna, biomarkers, epigenetics, microbiota, mirna
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

The pathogenesis of rheumatoid arthritis (RA) is incompletely understood. HLA class II alleles and T cells have been implicated for many years. The discovery of anticitrullinated peptide antibodies (ACPAs), along with the effectiveness of biological treatments targeting cytokines, such as TNF-?, IL-...