Huntington's Disease Molecular Pathogenesis and Current Models

• Outros Autores: Ersoy Tunalı, Nagehan (Editor)
• Formato: Recurso Eletrônico Capítulo de Livro
• Idioma: inglês
• Publicado em: IntechOpen 2017
• Assuntos: Neurology & clinical neurophysiology; huntington's disease, pluripotent stem cells, glutamate, creb, mouse models, mmr
• Acesso em linha: DOAB: download the publication; DOAB: description of the publication

Huntington's disease is a progressive neurodegenerative disorder of the brain. It is one of the quite devastating and currently incurable human conditions. Degeneration of specific types of neurons in the brain results in a triad of clinical features: serious behavioral disturbances, uncontroll...