Human Skin Cancers Pathways, Mechanisms, Targets and Treatments

• अन्य लेखक: Blumenberg, Miroslav (संपादक)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: IntechOpen 2018
• विषय: Oncology; biomarkers, immunotherapy, chemotherapy, melanoma, targeted therapy, squamous cell carcinoma
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

Human skin cancers, the most common type of tumors, represent a significant health burden. The deadliest is unquestionably melanoma. Half of melanomas have an activating mutation in the BRAF gene, prompting development of novel drugs, vemurafenib and dabrafenib, specifically targeting mutated BRAF....