Gene Expression and Regulation in Mammalian Cells Transcription From General Aspects

• Other Authors: Uchiumi, Fumiaki (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: IntechOpen 2018
• Subjects: Medical genetics; cancer, inflammation, breast cancer, melanoma, immunity, micrornas
• Online Access: DOAB: download the publication; DOAB: description of the publication

"Central dogma" was presented by Dr. Francis Crick 60 years ago. The information of nucleotide sequences on DNAs is transcribed into RNAs by RNA polymerases. We learned the mechanisms of how transcription determines function of proteins and behaviour of cells and even how it brings appeara...