Ubiquitin Proteasome System Current Insights into Mechanism Cellular Regulation and Disease

• Other Authors: Summers, Matthew (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: IntechOpen 2019
• Subjects: Proteins; cancer, ubiquitination, autophagy, immune system, dna damage, cell cycle
• Online Access: DOAB: download the publication; DOAB: description of the publication

The human ubiquitin proteasome system (UPS) is comprised of nearly 1000 proteins. Although originally identified as a mechanism of protein destruction, the UPS has numerous additional functions and mediates central signaling events in myriad processes involved in both cellular and organismal health...