Hsp90 Structure, Mechanism and Disease

• Other Authors: Prodromou, Chrisostomos (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Research & information: general; Biology, life sciences; Biochemistry; Hsp90; heat shock proteins; chaperone; structure; mechanism; regulation; disease; cancer; neurological disease; drug development
• Online Access: DOAB: download the publication; DOAB: description of the publication

The Hsp90 chaperone complex is responsible for the activation and maturation of a vast array of signaling proteins. Recently, there has been a leap in our understanding of the Hsp90 structure and molecular mechanisms involved in such regulation. This has opened a doorway to the underlying mechanisms...