Novel Approaches for Targeting Metalloproteinases

• अन्य लेखक: Santamaria, Salvatore (संपादक)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• विषय: Research & information: general; Biology, life sciences; Biochemistry; carbohydrates; glycoconjugates; MMPs; ADAMs; iminosugars; metzincin inhibitors; matrix metalloproteinases (MMPs), protease; tissue inhibitors of metalloproteinases (TIMPs), exosite; small molecule inhibitors; monoclonal antibodies; proteomics; N-terminomics; terminal amine isotopic labeling of substrates (TAILS); MMP-2; MMP-9; Alzheimer's disease; AD; neurodegeneration; neuroinflammation; natural compounds; marine compounds; terrestrial compounds; nutraceuticals; Matrix Metalloproteinase inhibitors; bone targeting; bisphosphonates; antitumor agents; skeletal malignancies; osteoarthritis; cartilage; metalloproteinase; targeting; meprin α; meprin β; zinc metalloproteinase; medicinal chemistry; probe development; uHTS; dipeptidyl peptidase III; coumarin derivatives; inhibitor; molecular modeling; β-blockers; carvedilol; matrix metalloproteinase-2; ischemia-reperfusion injury; isolated heart perfusion; kidney; obeticholic acid; ischemia/reperfusion; liver; metalloproteinases; MMP-2 inhibitor; cardiac dysfunction; ischemia; n/a
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

This Special Issue is a collection of eleven articles (five reviews and six studies) that describe a wide range of approaches to modulating metalloproteinase activity in disease. The techniques described are in vitro, in vivo, and ex vivo.