New Frontiers in Therapeutic Drug Monitoring of Biologics in Inflammatory Bowel Disease and Other Immune-Mediated Inflammatory Diseases

• Other Authors: Papamichael, Konstantinos (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Medicine; ulcerative colitis; Crohn’ s disease; inflammatory bowel disease; infliximab; adalimumab; certolizumab pegol; golimumab; vedolizumab; ustekinumab; therapeutic drug monitoring; immunogenicity; rheumatoid arthritis; ankylosing spondylitis; psoriasis; clearance; model informed precision dosing
• Online Access: DOAB: download the publication; DOAB: description of the publication

Therapeutic drug monitoring (TDM) has emerged as a useful tool for optimizing biological treatment in patients with inflammatory bowel disease (IBD) and other immune-mediated inflammatory diseases (IMID). Reactive TDM has rationalized the management of primary non-response and secondary loss of resp...