Solving the Puzzle: Molecular Research in Inflammatory Bowel Diseases

• Other Authors: Krug, Susanne M. (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: Medicine; inflammatory bowel diseases; cell autofluorescence; immune cells; NADH; FAD; flow cytometry; multiphoton microscopy; colitis; colitis-associated cancer; inflammatory bowel disease; colorectal cancer; colon adenocarcinoma; ulcerative colitis; Crohn's disease; cDNA microarray; transciptomics analysis; microarray; inflammatory bowel diseases (IBDs); vasculature; angiogenesis; gut vascular barrier; vessel permeability; epithelial barrier; homeostasis; acetylcholine; muscarinic receptor; non-neuronal acetylcholine; mucosal wound healing; ferroptosis; leaky gut; inflammatory bowel disease (IBD); triple-culture; Caco-2; HT29-MTX-E12; THP-1; monocyte-derived macrophage; inflammation; TEER; FITC-dextran 4 kDa (FD4); pro-inflammatory cytokines; HIF-1α; PHD2; AKT; intestinal epithelial cells; probiotics; LPS; antigen-specific T-cells; celiac disease; gliadin; IBD; food antigens; intestinal Behcet's disease; immune mechanism; biological agents; claudin; tight junctions; barrier function; gut; ZO-1; actin; cell migration; cell division; colon cancer; PMNs; LDs; FOXO3; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Inflammatory bowel disease (IBD) encompasses chronic idiopathic relapsing and remitting gastrointestinal autoimmune diseases characterized by chronic inflammatory disorders of complex etiology, posing clinical challenges due to their often therapy-refractory nature. The primary disorders within the...