Advances in Mechanisms of Renal Fibrosis

• Main Author: David J. Nikolic-Paterson (auth)
• Other Authors: Hui Y. Lan (auth)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2018
• Series: Frontiers Research Topics
• Subjects: Physiology; TGF-beta; fibroblast; JNK; miRNA; Smad; non-classical RAS; BMP7; HDAC; HIPK2
• Online Access: DOAB: download the publication; DOAB: description of the publication

Scarring of the glomerular and tubulointerstitial compartments is a hallmark of progressive kidney disease. Renal fibrosis involves a complex interplay between kidney cells, leukocytes and fibroblasts in which transforming growth factor-β (TGF-β) plays a key role. This eBook provides a comprehensive...