Advances in Mechanisms of Renal Fibrosis

• Hoofdauteur: David J. Nikolic-Paterson (auth)
• Andere auteurs: Hui Y. Lan (auth)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Frontiers Media SA 2018
• Reeks: Frontiers Research Topics
• Onderwerpen: Physiology; TGF-beta; fibroblast; JNK; miRNA; Smad; non-classical RAS; BMP7; HDAC; HIPK2
• Online toegang: DOAB: download the publication; DOAB: description of the publication

Scarring of the glomerular and tubulointerstitial compartments is a hallmark of progressive kidney disease. Renal fibrosis involves a complex interplay between kidney cells, leukocytes and fibroblasts in which transforming growth factor-β (TGF-β) plays a key role. This eBook provides a comprehensive...