Alterations of Epigenetics and MicroRNAs in Cancer and Cancer Stem Cell

• Yazar: Yoshimasa Saito (auth)
• Materyal Türü: Elektronik Kitap Bölümü
• Dil: İngilizce
• Baskı/Yayın Bilgisi: Frontiers Media SA 2014
• Seri Bilgileri: Frontiers Research Topics
• Konular: Genetics (non-medical); MicroRNAs; cancer stem cells; Methylation; epigenetics; Cancer
• Online Erişim: DOAB: download the publication; DOAB: description of the publication

Studies have shown that alterations of epigenetics and microRNAs (miRNAs) play critical roles in the initiation and progression of human cancer. Epigenetic silencing of tumor suppressor genes in cancer cells is generally mediated by DNA hypermethylation of CpG island promoter and histone modificatio...